FRYL and HOMER3

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)

		FRYL	HOMER3
Gene Name		FRY-like	homer homolog 3 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cellular_component Cytoplasm Cytosol Plasma Membrane Cell Junction Basal Part Of Cell Postsynaptic Membrane Neuronal Postsynaptic Density
	Molecular Function		Protein Binding Protein C-terminus Binding Protein Domain Specific Binding G-protein Coupled Glutamate Receptor Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Protein Targeting G-protein Coupled Glutamate Receptor Signaling Pathway Regulation Of Store-operated Calcium Entry
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: DISC1 HOMER3 PELI2	28 interactors: ABI2 ABI3 APP CEBPB DYNLL2 EAF1 EIF3D FAT1 FRYL GRM5 HOMER1 ITPR1 MOS NEBL PAX6 PKN1 POM121 PPP1R18 PSMA1 PSMA2 PSMC5 RUNX1T1 RYR1 SNRPF SRPK2 TRPC1 USP2 WIPF1
Entrez ID		285527	9454
HPRD ID		18995	07270
Ensembl ID		ENSG00000075539	ENSG00000051128
Uniprot IDs		B3KXG5 O94915 Q6ZR29	B2RA10 Q9NSC5
PDB IDs			2P8V 3CVF
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Cell Cycle Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Gene Expression Regulation Of Cell Cycle Phase Transition Regulation Of Protein Metabolic Process Regulation Of Cellular Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Glutamate Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Signaling Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Regulation Of Mitotic Cell Cycle Positive Regulation Of Ligase Activity Cell Communication DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To Stimulus Antigen Processing And Presentation Of Peptide Antigen Intracellular Signal Transduction Response To Stimulus Signal Transduction Single-organism Behavior Cell Differentiation Regulation Of Ubiquitin-protein Transferase Activity Movement Of Cell Or Subcellular Component Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic DNA Damage Checkpoint Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Process Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Arrest
Tagcloud ?		alkylating altering bilineage breakpoint conferred emergence etoposide fulfilled gd2 granulocyte harboring homologue joined junctions meis1 melanogaster metabolites mll multimodality oncoproteins p12 poisons protracted q23 reciprocal replaced topoisomerase translocation underexpressed	abetapp alzheimer analyzing assembly coil coiled deposition derivative emphasis evh1 generation herein importantly interacting interaction interacts manipulate metabolism offer plaques players polymerization possibly seems senile serine tail
Tagcloud (Difference) ?		alkylating altering bilineage breakpoint conferred emergence etoposide fulfilled gd2 granulocyte harboring homologue joined junctions meis1 melanogaster metabolites mll multimodality oncoproteins p12 poisons protracted q23 reciprocal replaced topoisomerase translocation underexpressed	abetapp alzheimer analyzing assembly coil coiled deposition derivative emphasis evh1 generation herein importantly interacting interaction interacts manipulate metabolism offer plaques players polymerization possibly seems senile serine tail
Tagcloud (Intersection) ?