DCAF4L1 and SHISA3

		DCAF4L1	SHISA3
Description		DDB1 and CUL4 associated factor 4 like 1	shisa family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cul4-RING E3 Ubiquitin Ligase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function		Protein Binding
	Biological Process		Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Helping behaviour (self reported) ( 29324852)	Anthracycline-induced cardiotoxicity in early breast cancer ( 32378780) Impulsivity (attentional) ( 30718321) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes			7 interacting genes: ANKRD46 CLDN11 CMTM7 MAL MEOX2 PNMA1 TMEM147
Entrez ID		285429	152573
HPRD ID		18775	19108
Ensembl ID		ENSG00000182308	ENSG00000178343
Uniprot IDs		Q3SXM0	A0PJX4
PDB IDs
Enriched GO Terms of Interacting Partners?			Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Protein Insertion Into Membrane Axon Ensheathment B-1a B Cell Differentiation Membrane Raft Polarization Protein Localization To Nuclear Inner Membrane Protein Localization To Paranode Region Of Axon B-1 B Cell Differentiation Peptidase Activator Activity Involved In Apoptotic Process Somite Specification
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