SHISA3 and ANKRD46

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SHISA3	ANKRD46
Description		shisa family member 3	ankyrin repeat domain 46
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Anthracycline-induced cardiotoxicity in early breast cancer ( 32378780) Impulsivity (attentional) ( 30718321) Type 2 diabetes (age of onset) ( 28060188)	Atrioventricular conduction ( 21041692) Body mass index ( 26426971) Percentage gas trapping ( 26030696)
Interacting Genes		7 interacting genes: ANKRD46 CLDN11 CMTM7 MAL MEOX2 PNMA1 TMEM147	63 interacting genes: AMIGO1 APH1A AQP6 ARL13B BIK BSCL2 C16orf54 CD22 CD46 CLDN20 CLDN7 CLEC4D CRB3 CREB3L1 CXADR CYB561 EBP EFNB1 EFNB2 ELOVL4 FAM174A FAM209A FFAR2 GOLM1 GPR152 GPR42 GPX8 HSD17B11 HSD17B13 IFNLR1 KASH5 KIR2DL3 LAMTOR5 LDLRAD1 LRRC25 MFF MMGT1 MUC1 NCAPH2 NSG2 PLPP4 PVR RELL2 RETREG3 SCN3B SECTM1 SHISA3 SLC10A6 SLC16A2 SLC18A1 SLC39A9 ST6GALNAC6 STX1A STX2 STX4 SUSD3 THAP4 TIMMDC1 TMEM248 TMEM31 TMEM45B TMEM79 TMPRSS2
Entrez ID		152573	157567
HPRD ID		19108	14103
Ensembl ID		ENSG00000178343	ENSG00000186106
Uniprot IDs		A0PJX4	B3KT99 Q86W74
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Protein Insertion Into Membrane Axon Ensheathment B-1a B Cell Differentiation Membrane Raft Polarization Protein Localization To Nuclear Inner Membrane Protein Localization To Paranode Region Of Axon B-1 B Cell Differentiation Peptidase Activator Activity Involved In Apoptotic Process Somite Specification	Membrane Protein Binding Plasma Membrane Steroid Dehydrogenase Activity
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