C3orf33 and TEX44

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C3orf33	TEX44
Description		chromosome 3 open reading frame 33	testis expressed 44
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Mitochondrion Membrane	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Focal epilepsy (with hippocampal sclerosis) ( 30531953)	Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		2 interacting genes: APP TEX44	13 interacting genes: APOC1 APP C3orf33 CIDEB COX20 CPT1B DERL1 MICOS13 MPC2 RHBDD2 SYPL1 TIMM17B TMEM14B
Entrez ID		285315	165100
HPRD ID		08095	14602
Ensembl ID		ENSG00000174928	ENSG00000177673
Uniprot IDs		Q6P1S2	Q53QW1
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding	Mitochondrial Inner Membrane Signal Recognition Particle Binding Very-low-density Lipoprotein Particle Assembly High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Plasma Lipoprotein Particle Assembly Intracellular Transport Membrane Mitochondrion Mitochondrial Transmembrane Transport Protein-lipid Complex Assembly Lipoprotein Metabolic Process Mitochondrial Transport Regulation Of Triglyceride Metabolic Process Negative Regulation Of Phosphatidylcholine Catabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Localization Establishment Of Localization In Cell Endoplasmic Reticulum Unfolded Protein Response Lipid Transport Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Pyruvate Import Into Mitochondria Derlin-1-VIMP Complex Regulation Of Phosphatidylcholine Catabolic Process PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Carnitine O-palmitoyltransferase Activity ERAD Pathway Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation
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