C3orf38 and SLC19A3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		C3orf38	SLC19A3
Gene Name		chromosome 3 open reading frame 38	solute carrier family 19 (thiamine transporter), member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Plasma Membrane Integral Component Of Membrane
	Molecular Function		Thiamine Uptake Transmembrane Transporter Activity
	Biological Process	Apoptotic Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Thiamine-containing Compound Metabolic Process Small Molecule Metabolic Process Thiamine Transmembrane Transport
Pathways			Metabolism of vitamins and cofactors Defective GIF causes intrinsic factor deficiency Defective CD320 causes methylmalonic aciduria Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Vitamin B1 (thiamin) metabolism Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs			L-Cysteine
Diseases
GWAS		Response to acetaminophen (hepatotoxicity) ( 21177773)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		1 interactors: SLC19A3	3 interactors: C3orf38 CREB3L4 TAB2
Entrez ID		285237	80704
HPRD ID		14509	07311
Ensembl ID		ENSG00000179021	ENSG00000135917
Uniprot IDs		D3DU39 E9PFZ1 Q5JPI3	F5H2M8 Q9BZV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Thiamine Transmembrane Transport Thiamine Transport Thiamine-containing Compound Metabolic Process Pyrimidine-containing Compound Transmembrane Transport Vitamin Transmembrane Transport Drug Transmembrane Transport Drug Transport Vitamin Transport Water-soluble Vitamin Metabolic Process Vitamin Metabolic Process Sulfur Compound Metabolic Process Response To Drug
Tagcloud ?			aza carrier colon cpg cytosine dac deacetylase deacetylation deoxycytidine epigenetic guanine hct116 ht29 islands markedly methylation methyltransferase possessing re solute sw48 sw480 thiamine thtr2 transporter transporters trichostatin tsa
Tagcloud (Difference) ?			aza carrier colon cpg cytosine dac deacetylase deacetylation deoxycytidine epigenetic guanine hct116 ht29 islands markedly methylation methyltransferase possessing re solute sw48 sw480 thiamine thtr2 transporter transporters trichostatin tsa
Tagcloud (Intersection) ?