C3orf38 and SLC19A3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		C3orf38	SLC19A3
Description		chromosome 3 open reading frame 38	solute carrier family 19 member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Thiamine Transmembrane Transporter Activity Vitamin Transmembrane Transporter Activity
	Biological Process	Apoptotic Process Positive Regulation Of Apoptotic Process	Thiamine Diphosphate Biosynthetic Process Thiamine Transport Pyridoxine Transport Thiamine-containing Compound Metabolic Process Vitamin Transport Transmembrane Transport Thiamine Transmembrane Transport
Pathways			Vitamin B1 (thiamin) metabolism
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Colorectal cancer ( 29228715) Diastolic blood pressure ( 27841878) Loneliness (multivariate analysis) ( 27629369) Response to acetaminophen (hepatotoxicity) ( 21177773) Systolic blood pressure ( 27841878) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Weight ( 34074324)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 30929738 31959851) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Obesity-related traits ( 23251661)
Interacting Genes		2 interacting genes: BAG4 SLC19A3	15 interacting genes: ARLN C3orf38 CREB3 CREB3L4 CYB561 CYP4F2 FXYD6-FXYD2 LAT PLPPR2 TAB2 THBD TMEM14A TMEM14B TMEM242 ZFPL1
Entrez ID		285237	80704
HPRD ID		14509	07311
Ensembl ID		ENSG00000179021	ENSG00000135917
Uniprot IDs		Q5JPI3	A0A2R8YHG5 Q9BZV2
PDB IDs			8S4U 8S5U 8S5W 8S5Z 8S61 8S62 8XV2 8XV5 8XV9 8Z7R 8Z7S 8Z7T 8Z7U 8Z7V 8Z7W 8Z7X 8Z7Y 9G5K
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of MRNA Modification Vitamin Transmembrane Transporter Activity Pyridoxine Transport Thiamine-containing Compound Metabolic Process Thiamine Transmembrane Transporter Activity Thiamine Transport Thiamine Diphosphate Metabolic Process Thiamine Diphosphate Biosynthetic Process Thiamine Transmembrane Transport Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Ruffle Assembly Azole Transmembrane Transport Pyrimidine-containing Compound Transmembrane Transport Adenyl-nucleotide Exchange Factor Activity Positive Regulation Of Fibroblast Migration Vitamin Transmembrane Transport Ruffle Organization Vitamin Metabolic Process Regulation Of Fibroblast Migration Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Stress Fiber Assembly Regulation Of Protein Targeting To Mitochondrion Response To Epidermal Growth Factor Positive Regulation Of Actin Filament Polymerization Pyrimidine-containing Compound Biosynthetic Process Vitamin Transport Positive Regulation Of Actin Filament Bundle Assembly Pyrimidine-containing Compound Metabolic Process Positive Regulation Of Protein Polymerization Organic Cation Transport Protein-folding Chaperone Binding Regulation Of Stress Fiber Assembly Negative Regulation Of MRNA Metabolic Process Cellular Response To Tumor Necrosis Factor Sulfur Compound Biosynthetic Process
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