FBXW12 and IL22RA1

Number of citations of the paper that reports this interaction (PubMedID 26171402)
27

		FBXW12	IL22RA1
Description		F-box and WD repeat domain containing 12	interleukin 22 receptor subunit alpha 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Plasma Membrane Membrane
	Molecular Function		Cytokine Receptor Activity Interferon Receptor Activity Protein Binding Interleukin-20 Binding Interleukin-22 Receptor Activity
	Biological Process	Protein Ubiquitination	Cytokine-mediated Signaling Pathway Negative Regulation Of Inflammatory Response Defense Response To Gram-negative Bacterium Interleukin-22-mediated Signaling Pathway
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Interleukin-20 family signaling
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		1 interacting genes: IL22RA1	2 interacting genes: FBXW12 IL22
Entrez ID		285231	58985
HPRD ID		16428	16108
Ensembl ID		ENSG00000164049	ENSG00000142677
Uniprot IDs		Q6X9E4	Q8N6P7
PDB IDs			3DGC 3DLQ 6DF3
Enriched GO Terms of Interacting Partners?		Interleukin-22 Receptor Activity Interferon Receptor Activity Interleukin-22-mediated Signaling Pathway Interleukin-20 Binding Cytokine Receptor Activity Defense Response To Gram-negative Bacterium	Interleukin-22 Receptor Binding
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