HYCC2 and PDCL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HYCC2	PDCL2
Description		hyccin PI4KA lipid kinase complex subunit 2	phosducin like 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane	Cytoplasm Endoplasmic Reticulum
	Molecular Function	Protein Binding
	Biological Process	Phosphatidylinositol Phosphate Biosynthetic Process Protein Localization To Plasma Membrane	Acrosome Assembly Protein Folding Spermatogenesis Spermatid Development Sperm Axoneme Assembly Cell Differentiation Flagellated Sperm Motility Sperm Flagellum Assembly
Pathways
Drugs
Diseases
GWAS			A body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 31562340) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		7 interacting genes: APP DAPK1 GOLGA2 MEOX1 PDCL2 TRIM27 TTC7B	5 interacting genes: GOLGA1 HYCC2 STEEP1 UNC13B YWHAB
Entrez ID		285172	132954
HPRD ID		11345	15109
Ensembl ID		ENSG00000155744	ENSG00000163440
Uniprot IDs		A0A804HIT6 B3KUG1 Q8IXS8	Q8N4E4
PDB IDs			3EVI
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Reproductive Process Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of NMDA Receptor Activity DAPK1-calmodulin Complex Regulation Of Autophagy Positive Regulation Of Autophagic Cell Death Positive Regulation Of Protein Glycosylation Negative Regulation Of Autophagy Sclerotome Development Somite Specification Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Positive Regulation Of Supramolecular Fiber Organization Regulation Of Toll Signaling Pathway Positive Regulation Of Autophagy Golgi Disassembly
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