WDR62 and THAP8

		WDR62	THAP8
Description		WD repeat domain 62	THAP domain containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Centriolar Satellite
	Molecular Function	Protein Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Neuroblast Proliferation Mitotic Spindle Organization Centriole Replication Nervous System Development Cerebral Cortex Development Neurogenesis Regulation Of Neuron Differentiation Regulation Of Centrosome Cycle Positive Regulation Of Neuron Migration
Pathways
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: DYRK2 ENKD1 LRIF1 MAGEB4 MAPK8 MAPK9 P4HA3 RALY TBC1D23 TBP	6 interacting genes: DYNLL1 NMI SETDB1 TFIP11 TMED9 TP53
Entrez ID		284403	199745
HPRD ID		10721	15501
Ensembl ID		ENSG00000075702	ENSG00000161277
Uniprot IDs		A0A7P0T9D9 A0A7P0TAK3 A0A7P0Z436 O43379	B4DKM9 H9CWI5 Q8NA92
PDB IDs
Enriched GO Terms of Interacting Partners?		JUN Kinase Activity Regulation Of RNA Metabolic Process MAP Kinase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Fc-epsilon Receptor Signaling Pathway Protein Serine/threonine/tyrosine Kinase Activity Nucleus Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process JUN Phosphorylation	Negative Regulation Of DNA Metabolic Process Negative Regulation Of DNA Replication Regulation Of DNA Metabolic Process Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Promoter-specific Chromatin Binding Negative Regulation Of Pentose-phosphate Shunt Organelle Organization Regulation Of Neuroblast Proliferation Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Site Of Double-strand Break Regulation Of DNA Replication Negative Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of Macromolecule Metabolic Process Germ Cell Nucleus Cellular Response To Actinomycin D Regulation Of Neural Precursor Cell Proliferation Deoxyribonuclease Inhibitor Activity Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Positive Regulation Of Protein K48-linked Ubiquitination Spliceosomal Complex Disassembly U2-type Post-mRNA Release Spliceosomal Complex Negative Regulation Of Metabolic Process Centrosome Histone Deacetylase Regulator Activity Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Response To Actinomycin D T Cell Proliferation Involved In Immune Response Cell Activation Involved In Immune Response Regulation Of G1 To G0 Transition Leukocyte Activation Involved In Immune Response Glial Cell Apoptotic Process Cellular Response To UV-C Negative Regulation Of Phosphate Metabolic Process ATP-dependent DNA/DNA Annealing Activity Negative Regulation Of Interferon-alpha Production Histone H3K9 Trimethyltransferase Activity DNA Metabolic Process B Cell Lineage Commitment Regulation Of Pentose-phosphate Shunt Regulation Of Protein K48-linked Ubiquitination Histone H3K9 Monomethyltransferase Activity COPI Coating Of Golgi Vesicle
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