RASSF3 and ITPRIP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RASSF3	ITPRIP
Description		Ras association domain family member 3	inositol 1,4,5-trisphosphate receptor interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Microtubule Plasma Membrane	Nucleus Nuclear Outer Membrane Plasma Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Kinase Inhibitor Activity Protein Binding
	Biological Process	Signal Transduction	Signal Transduction Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Signal Transduction Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS		Cardiometabolic and hematological traits ( 27668658) Lung adenocarcinoma ( 28604730) Lung function (FEV1/FVC) ( 30804560) Mean platelet volume ( 27863252 32888494) Platelet count ( 27863252 32888494) Prostate cancer ( 29892016) Resting heart rate ( 27798624 29769521)	Mean platelet volume ( 32888494)
Interacting Genes		14 interacting genes: APP CBX8 DAXX FAM110A ITPRIP KDM1A KYNU LITAF PARD6B RPRD1B TENT5D TFRC TRIM59 ZNF410	5 interacting genes: ITPR1 NLGN3 PGRMC2 RASSF3 SGTB
Entrez ID		283349	85450
HPRD ID		08448	13892
Ensembl ID		ENSG00000153179	ENSG00000148841
Uniprot IDs		Q86WH2	Q8IWB1
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Copper Ion Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Response To Manganese Ion Positive Regulation Of Macromolecule Metabolic Process Cellular Response To Copper Ion Nuclear Androgen Receptor Binding Neuron Maturation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Kynureninase Activity Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Metal Ion Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of RNA Metabolic Process Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Clathrin-coated Pit Protein Homodimerization Activity Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of DNA-templated Transcription Response To CAMP Positive Regulation Of Transcription By RNA Polymerase II Neuron Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress P53 Binding Cellular Response To Diamide Transferrin Receptor Activity Regulation Of Canonical NF-kappaB Signal Transduction Anthranilate Metabolic Process Response To Vitamin B6 Cytoplasmic Side Of Late Endosome Membrane Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity	Intracellularly Gated Calcium Channel Activity Platelet Dense Tubular Network Protein Homooligomerization Inositol 1,4,5-trisphosphate-gated Calcium Channel Activity Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Epithelial Fluid Transport Platelet Dense Granule Membrane Nuclear Envelope Protein Complex Oligomerization Calcium Ion Transmembrane Transporter Activity Platelet Dense Tubular Network Membrane Synapse Calcium Import Into The Mitochondrion Calcineurin Complex Voluntary Musculoskeletal Movement Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Inositol 1,4,5 Trisphosphate Binding Heme Transmembrane Transporter Activity Heme Transport Neurexin Family Protein Binding Asymmetric, Glutamatergic, Excitatory Synapse Regulation Of Respiratory Gaseous Exchange By Nervous System Process Inhibitory Postsynaptic Potential Positive Regulation Of Glutamate Receptor Signaling Pathway Rhythmic Synaptic Transmission Postsynaptic Membrane Assembly Postsynaptic Membrane Organization Presynaptic Membrane Assembly Regulation Of Glutamate Receptor Signaling Pathway Symmetric, GABA-ergic, Inhibitory Synapse Neuron To Neuron Synapse Presynapse Assembly Presynaptic Membrane Organization Post-translational Protein Targeting To Endoplasmic Reticulum Membrane TRC Complex Musculoskeletal Movement Calcium Channel Inhibitor Activity Regulation Of Respiratory System Process Neuron Cell-cell Adhesion Mitochondrial Calcium Ion Transmembrane Transport Presynapse Organization G Protein-coupled Acetylcholine Receptor Signaling Pathway Negative Regulation Of Calcium-mediated Signaling Vocalization Behavior Nuclear Steroid Receptor Activity Regulation Of Respiratory Gaseous Exchange Endoplasmic Reticulum Calcium Ion Homeostasis Protein Heterooligomerization
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