GP2 and SOX30

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		GP2	SOX30
Description		glycoprotein 2	SRY-box transcription factor 30
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endosome Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Cytoplasmic Vesicle Zymogen Granule Membrane Membrane Raft Extracellular Exosome Side Of Membrane	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Chromocenter
	Molecular Function	Antigen Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Beta-catenin Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Immune System Process Antigen Transcytosis By M Cells In Mucosal-associated Lymphoid Tissue Innate Immune Response Neutrophil Migration	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Spermatid Development Negative Regulation Of Wnt Signaling Pathway Response To Corticosteroid Positive Regulation Of Transcription By RNA Polymerase II Proacrosomal Vesicle Fusion
Pathways		Post-translational modification: synthesis of GPI-anchored proteins Developmental Lineage of Pancreatic Acinar Cells
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 22344219 24861553 28892062) Body size at age 10 ( 32376654) Chronic kidney disease ( 20383146) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Type 1 diabetes ( 34012112) Type 2 diabetes ( 30718926 32499647)	Glycated hemoglobin levels ( 28898252) Triglyceride levels ( 31647587)
Interacting Genes		6 interacting genes: AMY2A ANXA4 GLP1R JAGN1 SOX30 TSSK3	18 interacting genes: AHCYL1 AURKA BAMBI BRCA1 CFAP206 CUL5 DCAF4 DDX56 FBXO38 FHL2 FLI1 GNAI3 GP2 KIFC3 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		2813	11063
HPRD ID		04279	09461
Ensembl ID		ENSG00000169347	ENSG00000039600
Uniprot IDs		B7Z1G2 P55259	B4DXW7 O94993
PDB IDs		7P6R 7P6S 7P6T	7JJK
Enriched GO Terms of Interacting Partners?		Alpha-amylase Activity Hormone Secretion Hormone Transport Glucagon-like Peptide 1 Receptor Activity Spermatid Development Proacrosomal Vesicle Fusion Glucagon Receptor Activity Polysaccharide Digestion Response To Psychosocial Stress Signal Release Germ Cell Development Granulocyte Colony-stimulating Factor Signaling Pathway
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