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GNGT2 and KCNJ4
Number of citations of the paper that reports this interaction (PMID
8943291
)
5
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro, in vivo)
GNGT2
KCNJ4
Gene Name
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
potassium channel, inwardly rectifying subfamily J, member 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Heterotrimeric G-protein Complex
Plasma Membrane
Plasma Membrane
Voltage-gated Potassium Channel Complex
Basolateral Plasma Membrane
Cell Junction
Cytoplasmic Vesicle Membrane
Postsynaptic Membrane
Molecular Function
GTPase Activity
Signal Transducer Activity
Inward Rectifier Potassium Channel Activity
Protein Binding
PDZ Domain Binding
Biological Process
G-protein Coupled Receptor Signaling Pathway
Synaptic Transmission
Phototransduction
Metabolic Process
Potassium Ion Transport
Synaptic Transmission
Potassium Ion Import
Regulation Of Ion Transmembrane Transport
Pathways
Signaling by GPCR
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 1
Integration of energy metabolism
G alpha (s) signalling events
Activation of GABAB receptors
Glucagon-type ligand receptors
G beta:gamma signalling through PLC beta
Signaling by Wnt
Metabolic disorders of biological oxidation enzymes
G protein gated Potassium channels
Gastrin-CREB signalling pathway via PKC and MAPK
Thromboxane signalling through TP receptor
G alpha (z) signalling events
G alpha (i) signalling events
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
ADP signalling through P2Y purinoceptor 12
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Inwardly rectifying K+ channels
G-protein beta:gamma signalling
Opioid Signalling
Activation of Kainate Receptors upon glutamate binding
Aquaporin-mediated transport
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (q) signalling events
GPCR downstream signaling
Platelet homeostasis
Platelet activation, signaling and aggregation
Transmission across Chemical Synapses
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signal amplification
Potassium Channels
G beta:gamma signalling through PI3Kgamma
G alpha (12/13) signalling events
Class B/2 (Secretin family receptors)
Prostacyclin signalling through prostacyclin receptor
GABA B receptor activation
GABA receptor activation
Activation of G protein gated Potassium channels
Vasopressin regulates renal water homeostasis via Aquaporins
Regulation of insulin secretion
GPCR ligand binding
beta-catenin independent WNT signaling
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Ca2+ pathway
G-protein activation
GABA B receptor activation
Inwardly rectifying K+ channels
GABA receptor activation
Activation of G protein gated Potassium channels
Classical Kir channels
Activation of GABAB receptors
Potassium Channels
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
G protein gated Potassium channels
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
2 interactors:
GNB4
KCNJ4
10 interactors:
CASK
DLG1
DLG2
DLG4
GNGT2
IL16
KCNJ2
LIN7B
PRKCD
SNTA1
Entrez ID
2793
3761
HPRD ID
06792
02738
Ensembl ID
ENSG00000167083
ENSG00000168135
Uniprot IDs
O14610
P48050
Q58F07
PDB IDs
3GJ9
Enriched GO Terms of Interacting Partners
?
Receptor Localization To Synapse
Nucleotide Phosphorylation
Protein Localization To Synapse
Regulation Of Ion Transport
Establishment Or Maintenance Of Apical/basal Cell Polarity
Regulation Of Ion Transmembrane Transport
Cell-cell Signaling
Positive Regulation Of Ion Transport
Receptor Clustering
Synaptic Transmission
Maintenance Of Apical/basal Cell Polarity
Regulation Of Membrane Potential
Maintenance Of Cell Polarity
Protein Localization To Membrane
Regulation Of Actin Filament-based Process
Response To External Stimulus
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Regulation Of Membrane Repolarization
Cortical Actin Cytoskeleton Organization
Establishment Or Maintenance Of Cell Polarity
Nucleotide Metabolic Process
Cardiac Muscle Cell Action Potential Involved In Contraction
Positive Regulation Of Potassium Ion Transport
Cortical Cytoskeleton Organization
Negative Regulation Of Cell Adhesion
Nucleobase-containing Small Molecule Metabolic Process
Regulation Of Sodium Ion Transmembrane Transport
Cardiac Muscle Cell Action Potential
Muscle System Process
Regulation Of Cardiac Muscle Cell Contraction
Positive Regulation Of Transport
Membrane Organization
Regulation Of Potassium Ion Transport
Negative Regulation Of Wound Healing
Regulation Of Sodium Ion Transport
Positive Regulation Of Phospholipid Scramblase Activity
Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential
Positive Regulation Of Glucosylceramide Catabolic Process
Positive Regulation Of Sphingomyelin Catabolic Process
Regulation Of Vasoconstriction By Circulating Norepinephrine
Regulation Of Heart Rate
Regulation Of Cardiac Muscle Contraction
Positive Regulation Of Ion Transmembrane Transport
Phosphorylation
Organophosphate Metabolic Process
Regulation Of Striated Muscle Contraction
Action Potential
Protein Stabilization
Negative Regulation Of Homotypic Cell-cell Adhesion
Relaxation Of Skeletal Muscle
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Tagcloud (Difference)
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Tagcloud (Intersection)
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