GNGT1 and ZNF277

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GNGT1	ZNF277
Gene Name		guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	zinc finger protein 277
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Inner Segment Heterotrimeric G-protein Complex Plasma Membrane Photoreceptor Disc Membrane	Nucleus
	Molecular Function	GTPase Activity Signal Transducer Activity	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Signal Transduction Synaptic Transmission Phototransduction, Visible Light Protein Localization Metabolic Process Cardiac Muscle Cell Apoptotic Process Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Eye Photoreceptor Cell Development Cellular Response To Hypoxia	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To Hydrogen Peroxide Regulation Of Cellular Senescence
Pathways		Signaling by GPCR Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 1 Integration of energy metabolism Activation of GABAB receptors G alpha (s) signalling events Glucagon-type ligand receptors G beta:gamma signalling through PLC beta Signaling by Wnt Metabolic disorders of biological oxidation enzymes G protein gated Potassium channels Olfactory Signaling Pathway Gastrin-CREB signalling pathway via PKC and MAPK Thromboxane signalling through TP receptor G alpha (z) signalling events G alpha (i) signalling events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell ADP signalling through P2Y purinoceptor 12 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Inwardly rectifying K+ channels G-protein beta:gamma signalling Opioid Signalling Activation of Kainate Receptors upon glutamate binding Diseases associated with visual transduction Aquaporin-mediated transport Adrenaline,noradrenaline inhibits insulin secretion G alpha (q) signalling events GPCR downstream signaling Platelet homeostasis Platelet activation, signaling and aggregation Transmission across Chemical Synapses G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signal amplification Potassium Channels Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade G beta:gamma signalling through PI3Kgamma The phototransduction cascade G alpha (12/13) signalling events Class B/2 (Secretin family receptors) Prostacyclin signalling through prostacyclin receptor GABA B receptor activation GABA receptor activation Activation of G protein gated Potassium channels Vasopressin regulates renal water homeostasis via Aquaporins Regulation of insulin secretion GPCR ligand binding beta-catenin independent WNT signaling Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Visual phototransduction Ca2+ pathway G-protein activation
Drugs
Diseases
GWAS			Breast size ( 22747683)
Protein-Protein Interactions		10 interactors: GNAS GNB1 GNB2 GNB4 GNB5 IKBKG NAGA PLEKHB1 RHO ZNF277	7 interactors: COIL DDB1 GNGT1 MBD3 NUTM1 ZBTB7B ZNF768
Entrez ID		2792	11179
HPRD ID		01805	05680
Ensembl ID		ENSG00000127928	ENSG00000198839
Uniprot IDs		P63211	Q9NRM2
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Glucagon Stimulus Response To Glucagon Phototransduction Detection Of Light Stimulus Regulation Of Rhodopsin Mediated Signaling Pathway Energy Reserve Metabolic Process Rhodopsin Mediated Signaling Pathway Detection Of Abiotic Stimulus Phototransduction, Visible Light Energy Derivation By Oxidation Of Organic Compounds Cellular Response To Peptide Hormone Stimulus Detection Of Visible Light Cellular Response To Peptide Cellular Response To Light Stimulus Response To Light Stimulus Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Cellular Response To Prostaglandin E Stimulus Generation Of Precursor Metabolites And Energy Cellular Response To Radiation Response To Radiation Response To Peptide Hormone Cellular Response To Prostaglandin Stimulus Response To Prostaglandin E Cellular Response To Organonitrogen Compound Response To Peptide Regulation Of G-protein Coupled Receptor Protein Signaling Pathway G-protein Coupled Receptor Signaling Pathway Cellular Response To Catecholamine Stimulus Detection Of Stimulus Cellular Response To Hormone Stimulus Cellular Response To Stimulus Dopamine Receptor Signaling Pathway Cellular Response To Fatty Acid Signal Transduction Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Response To Organonitrogen Compound Signaling Cell Communication Response To Fatty Acid Response To Hormone Post-embryonic Body Morphogenesis Red, Far-red Light Phototransduction Response To External Stimulus Response To Stimulus Cell Surface Receptor Signaling Pathway Response To Abiotic Stimulus Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Retina Development In Camera-type Eye	Cellular Response To Light Stimulus Cellular Response To Radiation Positive Regulation By Virus Of Viral Protein Levels In Host Cell UV-damage Excision Repair Methylation-dependent Chromatin Silencing Positive Regulation Of Viral Release From Host Cell Cardiac Muscle Cell Apoptotic Process Response To Light Stimulus Muscle Cell Apoptotic Process Histone H2A Monoubiquitination Histone Modification Histone H2A Ubiquitination Response To Radiation Nucleotide-excision Repair, DNA Damage Removal Histone Monoubiquitination Positive Regulation Of Viral Genome Replication Regulation Of Viral Release From Host Cell Ectoderm Development Regulation Of Rhodopsin Mediated Signaling Pathway Nucleobase-containing Compound Metabolic Process Chromatin Modification Rhodopsin Mediated Signaling Pathway Interaction With Symbiont Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Silencing Histone Ubiquitination Transcription, DNA-templated Eye Photoreceptor Cell Development Cellular Nitrogen Compound Metabolic Process Chromatin Organization RNA Biosynthetic Process Protein Monoubiquitination Photoreceptor Cell Development Eye Photoreceptor Cell Differentiation
Tagcloud ?			7q31 allelotyping chromosome d7s2502 d7s525 deletions diploid dock4 duplication elucidating elusive evolutionarily finger head hel hemizygous heterozygosity implicating island karyotypically localize loci ml3 monosomy myelodysplasia myelogenous portends preleukemic reagents
Tagcloud (Difference) ?			7q31 allelotyping chromosome d7s2502 d7s525 deletions diploid dock4 duplication elucidating elusive evolutionarily finger head hel hemizygous heterozygosity implicating island karyotypically localize loci ml3 monosomy myelodysplasia myelogenous portends preleukemic reagents
Tagcloud (Intersection) ?