ERLEC1 and CIMIP6

		ERLEC1	CIMIP6
Description		endoplasmic reticulum lectin 1	ciliary microtubule inner protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Quality Control Compartment	Cilium Cell Projection
	Molecular Function	Protein Binding Unfolded Protein Binding
	Biological Process	Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		1 interacting genes: STK11	3 interacting genes: FCHSD2 HSPB1 SH3BP4
Entrez ID		27248	129852
HPRD ID		10310	13446
Ensembl ID		ENSG00000068912	ENSG00000177994
Uniprot IDs		Q96DZ1 V9HWD3	Q8N5S3
PDB IDs		8KES 8KET 8KEV
Enriched GO Terms of Interacting Partners?			Intracellular Protein Localization Clathrin-coated Pit Unfolded Protein Binding Negative Regulation Of Protein Kinase C Signaling Stereocilium Shaft Protein Kinase C Inhibitor Activity Amino Acid Import Protein Transport Regulation Of Protein Kinase C Signaling Establishment Of Protein Localization Protein Transport Along Microtubule Anterograde Axonal Protein Transport Contractile Muscle Fiber Regulation Of Autophagy Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Protein Exit From Endoplasmic Reticulum Positive Regulation Of Endothelial Cell Chemotaxis GDP-dissociation Inhibitor Activity Negative Regulation Of GTPase Activity Endocytosis Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Exit From Endoplasmic Reticulum Intracellular Protein Transport Endoplasmic Reticulum Quality Control Compartment Protein Refolding Phosphatidylinositol-3,4-bisphosphate Binding Regulation Of Arp2/3 Complex-mediated Actin Nucleation
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