ERLEC1

Description		endoplasmic reticulum lectin 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding Unfolded Protein Binding
	Biological Process	Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Novel Interacting Genes		3 novel interacting genes: CIMIP6 RPL23AP32 TSPYL6
Interacting Genes		1 interacting genes: STK11
Entrez ID		27248
HPRD ID		10310
Ensembl ID		ENSG00000068912
Uniprot IDs		Q96DZ1 V9HWD3
PDB IDs		8KES 8KET 8KEV
Enriched GO Terms of Interacting Partners?
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