TUBGCP4 and ADD3

		TUBGCP4	ADD3
Description		tubulin gamma complex component 4	adducin 3
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Gamma-tubulin Complex Gamma-tubulin Ring Complex Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Microtubule Cytoskeleton Membrane Recycling Endosome	Condensed Nuclear Chromosome Cytoplasm Cytosol Cytoskeleton Plasma Membrane Brush Border Cell-cell Junction Cell Cortex Postsynaptic Density Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	Actin Binding Protein Kinase C Binding Structural Constituent Of Cytoskeleton Calmodulin Binding Actin Filament Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly	Cytoskeleton Organization Response To Xenobiotic Stimulus Positive Regulation Of Vasoconstriction Barbed-end Actin Filament Capping Positive Regulation Of Cytoskeleton Organization
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Miscellaneous transport and binding events RHOD GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Glycine levels ( 30837465) HDL cholesterol ( 30275531) Liver enzyme levels (alkaline phosphatase) ( 33972514) Triglycerides ( 30275531)	Biliary atresia ( 20460270) Bipolar disorder ( 28072414 31043756 33263727 34002096) Cutaneous melanoma or hair colour ( 32341527) Metabolite levels ( 23823483) Neutrophil count ( 29403010) Refractive error ( 32231278) White blood cell count ( 29403010)
Interacting Genes		32 interacting genes: ADAMTSL4 AP2B1 CBY2 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 FDXACB1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 KRT4 KRT6B LZTR1 MAD1L1 NUDT3 PAK5 PHKA1 RNF146 RPRD1B SDSL STN1 TRIM27 TRIM55 TRIM63 TUBG1 USHBP1 VIM	7 interacting genes: AGTR1 ATXN1 HSPB1 OPRM1 PRKCA SIM2 UBE2I
Entrez ID		27229	120
HPRD ID		10616	03339
Ensembl ID		ENSG00000137822	ENSG00000148700
Uniprot IDs		Q9UGJ1	Q53FL4 Q59EK1 Q5VU08 Q9UEY8
PDB IDs		3RIP 6V69 6V6S 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 7QJE 8Q62 8RX1 8VRD 8VRJ 8VRK
Enriched GO Terms of Interacting Partners?		Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Cytoskeleton Intermediate Filament Organization Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Identical Protein Binding Bergmann Glial Cell Differentiation Structural Constituent Of Skin Epidermis Scaffold Protein Binding Microtubule Astrocyte Development	G Protein-coupled Opioid Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway G-protein Beta-subunit Binding Nuclear Body Angiotensin Type I Receptor Activity System Process Negative Regulation Of Protein Kinase C Signaling Morphine Receptor Activity Nervous System Process Sensory Perception Of Pain Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Synaptic Vesicle Lumen Nuclear Membrane Organization SUMO Conjugating Enzyme Activity RNA Lariat Debranching Enzyme Activator Activity
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