KCNMB3 and NAP1L1

		KCNMB3	NAP1L1
Description		potassium calcium-activated channel subfamily M regulatory beta subunit 3	nucleosome assembly protein 1 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane	Chromatin Nucleus Cytoplasm Membrane Melanosome
	Molecular Function	Calcium-activated Potassium Channel Activity Potassium Channel Regulator Activity	Chromatin Binding RNA Binding Protein Binding Histone Binding Histone Chaperone Activity
	Biological Process	Action Potential Detection Of Calcium Ion Monoatomic Ion Transport Potassium Ion Transport Neuronal Action Potential Monoatomic Ion Transmembrane Transport Potassium Ion Transmembrane Transport	DNA Replication Nucleosome Assembly Nervous System Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Ca2+ activated K+ channels cGMP effects
Drugs		Procaine Ritodrine Nitrendipine Miconazole Colforsin Trimebutine
Diseases
GWAS			Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)
Interacting Genes			34 interacting genes: ANKRD23 C1QTNF9 CHORDC1 CREBBP CSNK2A1 CSNK2B DLST DYRK1A EP300 ERCC6 FSD1 GAS2L2 H1-1 H4C1 HBA1 HMGB2 HSPB1 ISG15 LINC01554 MED10 MTNR1A NAP1L2 NR2F6 OGT POT1 RPL23 RPL23A RPS15 SNCA SP1 SUMO2 TERF1 TP53 TPX2
Entrez ID		27094	4673
HPRD ID		05563	01248
Ensembl ID		ENSG00000171121	ENSG00000187109
Uniprot IDs		Q9NPA1	B7Z2V4 F5H4R6 F8W543 P55209 Q9H2B0
PDB IDs			7BP5 7UN3 7UN6
Enriched GO Terms of Interacting Partners?		Histone Chaperone Activity	Rhythmic Process Regulation Of Protein Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Nucleoplasm Negative Regulation Of DNA Metabolic Process Nucleus Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cellular Response To Stress Regulation Of Cellular Response To Heat Transcription Coactivator Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Histone H3K27 Acetyltransferase Activity Tau Protein Binding Negative Regulation Of Cellular Component Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Histone H3K18 Acetyltransferase Activity Double-strand Break Repair N-terminal Peptidyl-lysine Acetylation Chromatin Remodeling Cellular Component Assembly Peptide Lactyltransferase (CoA-dependent) Activity Chromatin Organization Regulation Of Cellular Component Organization Protein Localization To Organelle Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Double-strand Break Repair Via Nonhomologous End Joining Symbiont-mediated Disruption Of Host Cell PML Body Circadian Rhythm Negative Regulation Of Telomere Maintenance Via Telomerase Cellular Response To Actinomycin D Negative Regulation Of Proteolysis Positive Regulation Of Metabolic Process Histone Acetyltransferase Complex Negative Regulation Of Catabolic Process Regulation Of Proteolysis Regulation Of Microtubule-based Process Response To Actinomycin D Regulation Of Primary Metabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Amide Metabolic Process Regulation Of Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Chromatin DNA Binding Regulation Of Protein-containing Complex Assembly Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of G1 To G0 Transition
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