NARF and LMNA

Number of citations of the paper that reports this interaction (PMID 10514485)
25

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		NARF	LMNA
Gene Name		nuclear prelamin A recognition factor	lamin A/C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Lamin Filament Nuclear Lamina Nucleolus Nuclear Lumen	Nucleus Nuclear Envelope Lamin Filament Nuclear Lamina Nucleoplasm Cytoplasm Cytosol Intermediate Filament Nuclear Speck Perinuclear Region Of Cytoplasm
	Molecular Function	Lamin Binding	Structural Molecule Activity Protein Binding
	Biological Process		Mitotic Cell Cycle Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Mitotic Nuclear Envelope Disassembly Mitotic Nuclear Envelope Reassembly Muscle Organ Development Regulation Of Cell Migration Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Endoplasmic Reticulum Unfolded Protein Response Protein Localization To Nucleus Sterol Regulatory Element Binding Protein Import Into Nucleus Cellular Protein Metabolic Process Ventricular Cardiac Muscle Cell Development Cellular Response To Hypoxia Negative Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Cell Aging Regulation Of Protein Localization To Nucleus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APP LEF1 LMNA STAT5A	43 interactors: ACTB ALOX12 ALOX12B CASP1 CASP6 CDK1 DBNL DUSP13 EGF EMD FLNA FOS GZMA GZMB KAT5 KRTAP10-3 KRTAP10-7 LMNB1 MLIP MRPS26 NARF PCBP1 PCGF2 PRKCA RB1 RBBP4 SH3KBP1 SMAD3 SREBF1 STAC SUMO4 SVIL SYNE1 TMPO TOR1A TOR1AIP1 UBE2I UCHL5 UNC13D URB2 VAV1 YWHAQ ZNF239
Entrez ID		26502	4000
HPRD ID		05637	01035
Ensembl ID		ENSG00000141562	ENSG00000160789
Uniprot IDs		Q9UHQ1	P02545
PDB IDs			1IFR 1IVT 1X8Y 2XV5 2YPT 3GEF 3V4Q 3V4W 3V5B
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Myeloid Cell Differentiation Regulation Of Growth Regulation Of Protein Metabolic Process Cell Activation Regulation Of Multicellular Organism Growth Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Sterol Regulatory Element Binding Protein Import Into Nucleus Positive Regulation Of Mast Cell Differentiation Hormone-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Regulation Of Protein Binding Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle T Cell Differentiation Striated Muscle Cell Development Organ Development Apoptotic Process Negative Regulation Of Cell Death Mammary Gland Development Programmed Cell Death Muscle Cell Development Regulation Of Myeloid Cell Differentiation Synaptic Growth At Neuromuscular Junction Negative Regulation Of Apoptotic Process In Bone Marrow Cell Death Death Cell Differentiation Positive Regulation Of Metabolic Process Neutrophil Differentiation Negative Regulation Of Estrogen Receptor Binding Collateral Sprouting In Absence Of Injury Regulation Of Mast Cell Differentiation Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Development Of Secondary Male Sexual Characteristics Cell Adhesion Positive Regulation Of Growth Positive Regulation Of Cell Cycle Process Positive Regulation Of Protein Metabolic Process Striated Muscle Cell Differentiation Lymphocyte Differentiation	Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Protein Localization Regulation Of Cellular Localization Positive Regulation Of Transport Nucleus Organization Nuclear Envelope Organization Regulation Of Signaling Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Regulation Of Signal Transduction Organelle Organization Positive Regulation Of Nucleocytoplasmic Transport Enzyme Linked Receptor Protein Signaling Pathway Response To Stress Cellular Response To Growth Factor Stimulus Positive Regulation Of Signal Transduction Response To Growth Factor Immune Response Cellular Response To Organic Substance Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Transport Regulation Of Catenin Import Into Nucleus Epidermal Growth Factor Receptor Signaling Pathway Execution Phase Of Apoptosis ERBB Signaling Pathway Positive Regulation Of Proteolysis Regulation Of Protein Import Into Nucleus Positive Regulation Of Cellular Protein Metabolic Process Organ Development Cellular Response To Stimulus Response To Wounding Platelet Activation Regulation Of Protein Localization To Nucleus Positive Regulation Of Protein Transport Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Anatomical Structure Development Regulation Of Nucleocytoplasmic Transport Immune System Process Nuclear Membrane Organization Mitotic Nuclear Envelope Disassembly Intracellular Signal Transduction Positive Regulation Of Protein Localization To Nucleus Hepoxilin Metabolic Process Hepoxilin Biosynthetic Process
Tagcloud ?			1824c acro affiliated alopecia bossing chin clavicles contracture extremities g608g gilford groove hgps horse huazhong hutchinson joints micrognathia midline osteolysis phalanges progeria radiographical riding sclerodermatous stance stature tongji x10
Tagcloud (Difference) ?			1824c acro affiliated alopecia bossing chin clavicles contracture extremities g608g gilford groove hgps horse huazhong hutchinson joints micrognathia midline osteolysis phalanges progeria radiographical riding sclerodermatous stance stature tongji x10
Tagcloud (Intersection) ?