CHTOP and PHLDB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CHTOP	PHLDB3
Description		chromatin target of PRMT1	pleckstrin homology like domain family B member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nucleoplasm Nucleolus Nuclear Speck
	Molecular Function	RNA Binding Protein Binding Methyl-CpG Binding	Protein Binding Enzyme Binding
	Biological Process	In Utero Embryonic Development Chromatin Remodeling MRNA Export From Nucleus Positive Regulation Of ATP-dependent Activity MRNA Transport Positive Regulation Of Helicase Activity
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: APOBEC3C APP CEBPA GSK3A KHDRBS2 PHLDB3 RBM3 SMN1 SMN2 SNRPA SRPK2	3 interacting genes: CHTOP MDM2 TPM3
Entrez ID		26097	653583
HPRD ID		13163
Ensembl ID		ENSG00000160679	ENSG00000176531
Uniprot IDs		A0A087X1B7 Q9Y3Y2	Q6NSJ2 Q96HZ0
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Spliceosomal Complex Assembly Positive Regulation Of Neuron Apoptotic Process RNA Metabolic Process RNA Processing MRNA Processing SMN Complex Gemini Of Cajal Bodies MRNA Metabolic Process Response To Lithium Ion Cellular Response To Lithium Ion Regulation Of MRNA Splicing, Via Spliceosome SMN-Sm Protein Complex Positive Regulation Of Gene Expression DNA-templated Transcription Termination RNA Splicing Regulation Of MRNA Processing Axon Perikaryon Positive Regulation Of Amyloid Precursor Protein Catabolic Process Nucleus Nucleic Acid Metabolic Process Cellular Response To Metal Ion Regulation Of RNA Splicing Protein-RNA Complex Assembly Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process RNA Splicing, Via Transesterification Reactions Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Spliceosomal SnRNP Assembly Negative Regulation Of Viral Genome Replication Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Regulation Of Neuron Apoptotic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Nucleobase-containing Compound Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of UDP-glucose Catabolic Process Chromatin Remodeling Epigenetic Regulation Of Gene Expression Cajal Body Regulation Of Carbohydrate Catabolic Process Macromolecule Metabolic Process Acetylcholine Receptor Activator Activity Response To Metal Ion Lipoprotein Particle	Response To Vitamin B1 NEDD8 Ligase Activity Response To Actinomycin D Response To Water-immersion Restraint Stress Response To Formaldehyde Cellular Response To Vitamin B1 Traversing Start Control Point Of Mitotic Cell Cycle Cellular Response To Actinomycin D Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Muscle Thin Filament Tropomyosin Positive Regulation Of Helicase Activity Cellular Response To UV-C Receptor Serine/threonine Kinase Binding Atrial Septum Development Fibroblast Activation Peroxisome Proliferator Activated Receptor Binding Cellular Response To Antibiotic 5S RRNA Binding Transcription Export Complex SUMO Transferase Activity Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Cellular Response To Estrogen Stimulus Endocardial Cushion Morphogenesis Response To Ether Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Magnesium Ion Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Protein Export From Nucleus Response To Immobilization Stress Heart Valve Development Atrioventricular Valve Morphogenesis Response To UV-C Negative Regulation Of Protein Processing Negative Regulation Of Protein Maturation Supramolecular Fiber Organization Positive Regulation Of ATP-dependent Activity Disordered Domain Specific Binding Methyl-CpG Binding Cellular Response To Gamma Radiation Amyloid Fibril Formation Response To Iron Ion Ventricular Septum Development Postsynaptic Modulation Of Chemical Synaptic Transmission Regulation Of ATP-dependent Activity Cellular Response To Nutrient Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Protein Export From Nucleus Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To Alkaloid
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