CNTNAP2 and CTR9

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CNTNAP2	CTR9
Gene Name		contactin associated protein-like 2	CTR9, Paf1/RNA polymerase II complex component
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Golgi Apparatus Voltage-gated Potassium Channel Complex Cell Surface Membrane Integral Component Of Membrane Axon Dendrite Axolemma Neuronal Cell Body Perikaryon Juxtaparanode Region Of Axon	Cdc73/Paf1 Complex Nuclear Speck Transcriptionally Active Chromatin
	Molecular Function	Enzyme Binding	RNA Polymerase II Core Binding Protein Binding SH2 Domain Binding
	Biological Process	Cell Adhesion Brain Development Learning Neuron Recognition Transmission Of Nerve Impulse Striatum Development Limbic System Development Thalamus Development Cerebral Cortex Development Adult Behavior Neuron Projection Development Cellular Protein Localization Social Behavior Clustering Of Voltage-gated Potassium Channels Superior Temporal Gyrus Development Protein Localization To Juxtaparanode Region Of Axon Vocalization Behavior	Negative Regulation Of Transcription From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Transcription, DNA-templated JAK-STAT Cascade Histone Monoubiquitination Wnt Signaling Pathway Stem Cell Maintenance Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2B Ubiquitination Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Interleukin-6-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Histone H3-K4 Trimethylation Positive Regulation Of Histone H3-K79 Methylation
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 22159054) Bipolar disorder and schizophrenia ( 20889312) Body mass index (interaction) ( 23192594) Bone mineral density ( 17903296) Obesity-related traits ( 23251661) QT interval (interaction) ( 23459443) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		8 interactors: CASK CNTN2 CTR9 EPB41L3 KCNA2 MACF1 MEOX2 ZMIZ1	6 interactors: BLK CNTNAP2 HIST1H1C KMT2A SMAD9 TCEA1
Entrez ID		26047	9646
HPRD ID		05197	06717
Ensembl ID		ENSG00000174469	ENSG00000198730
Uniprot IDs		B2RCH4 Q9UHC6	Q6PD62
PDB IDs
Enriched GO Terms of Interacting Partners?		Anatomical Structure Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Multicellular Organismal Development Anatomical Structure Development Developmental Process System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Formation Involved In Morphogenesis Embryo Development Establishment Of Protein Localization To Juxtaparanode Region Of Axon Regulation Of Cell Morphogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Adenosine Receptor Signaling Pathway Optic Nerve Structural Organization Vitellogenesis Positive Regulation Of Histone H3-K79 Methylation Regulation Of Cell-matrix Adhesion Formation Of Primary Germ Layer Positive Regulation Of Macromolecule Biosynthetic Process Clustering Of Voltage-gated Potassium Channels Positive Regulation Of Gene Expression Myelination Protein Localization To Plasma Membrane Axon Ensheathment Positive Regulation Of Cellular Biosynthetic Process Regulation Of Axonogenesis Gastrulation Regulation Of Cell-substrate Adhesion Protein Localization To Paranode Region Of Axon Somite Specification Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Axon Diameter Membrane Organization Plasma Membrane Organization Cell Differentiation Regulation Of Cellular Component Organization Positive Regulation Of Metabolic Process Posttranslational Protein Targeting To Membrane Cytoplasm Organization Cerebral Cortex GABAergic Interneuron Migration Histone H2B Ubiquitination Regulation Of Cell Projection Size Interneuron Migration From The Subpallium To The Cortex Optic Nerve Morphogenesis Presynaptic Membrane Organization Wnt Signaling Pathway Cytoskeletal Anchoring At Plasma Membrane Negative Regulation Of Keratinocyte Proliferation Neuronal Ion Channel Clustering Paranodal Junction Assembly	Organ Development Positive Regulation Of Cellular Response To Drug Hemopoiesis Immune System Development Superior Temporal Gyrus Development Regulation Of Histone H3-K14 Acetylation Regulation Of Cellular Response To Drug Clustering Of Voltage-gated Potassium Channels System Development Regulation Of Response To Drug Multicellular Organismal Development Nucleosome Positioning Mullerian Duct Regression Anatomical Structure Development Protein Localization To Juxtaparanode Region Of Axon Neuronal Ion Channel Clustering Positive Regulation Of Transcription, DNA-templated Histone H3-K4 Trimethylation Regulation Of Histone H3-K9 Acetylation Developmental Process Histone H4-K16 Acetylation Thalamus Development Positive Regulation Of Histone H3-K4 Methylation Vocalization Behavior Striatum Development Positive Regulation Of Macromolecule Biosynthetic Process Anatomical Structure Regression Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Histone H3-K4 Methylation Subpallium Development Peptidyl-lysine Trimethylation
Tagcloud ?		acutely ameliorate asd autism cdfe contactin deficit deficits designer displays dreadd dysregulation epilepsy exclusively homolog hypothalamus immunoreactive knockout lasting melanocortin neuropeptide neuropsychiatric oxytocin paraventricular penetrance pvn rectify rescued windows	antiparallel assembling assembly binds biochemical conserved coordinated detailed diverse elongation embryonic heterodimer histone identity leo1 maintenance modifications nucleosome octamer paf1 paf1c posttranscriptional recognition reveals scaffold shed sheet subcomplex tightly
Tagcloud (Difference) ?		acutely ameliorate asd autism cdfe contactin deficit deficits designer displays dreadd dysregulation epilepsy exclusively homolog hypothalamus immunoreactive knockout lasting melanocortin neuropeptide neuropsychiatric oxytocin paraventricular penetrance pvn rectify rescued windows	antiparallel assembling assembly binds biochemical conserved coordinated detailed diverse elongation embryonic heterodimer histone identity leo1 maintenance modifications nucleosome octamer paf1 paf1c posttranscriptional recognition reveals scaffold shed sheet subcomplex tightly
Tagcloud (Intersection) ?