SPATS2L and PPIL3

		SPATS2L	PPIL3
Description		spermatogenesis associated serine rich 2 like	peptidylprolyl isomerase like 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Protein-containing Complex	Nucleoplasm Spliceosomal Complex Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Isomerase Activity
	Biological Process		MRNA Splicing, Via Spliceosome MRNA Processing Protein Folding RNA Splicing
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) Asthma (bronchodilator response) ( 22792082) Atrial fibrillation ( 30061737 29892015) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 33169155) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting plasma glucose ( 32682390) FEV1 ( 30804560) Household income (MTAG) ( 31844048) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560) Pelvic organ prolapse ( 26545240) QT interval ( 24952745) QT interval (sulfonylurea treatment interaction) ( 27958378) Reaction time ( 27046643 29844566) Schizophrenia ( 23974872 30285260 29483656 28991256) Schizophrenia (MTAG) ( 32107650) Sleep duration ( 30846698) Systolic blood pressure ( 30224653) Urate levels in lean individuals ( 25811787) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)	Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Triptolide cytotoxicity ( 26121980)
Interacting Genes		5 interacting genes: CSNK2A1 EEF1A1 OGT RBFOX2 ZRSR2	10 interacting genes: CENATAC DMRTB1 PCBP1 PHC1 RPS13 SHARPIN SLU7 TAB2 TAB3 YTHDF1
Entrez ID		26010	53938
HPRD ID		10916	15163
Ensembl ID		ENSG00000196141	ENSG00000240344
Uniprot IDs		B8ZZZ7 Q9NUQ6	A0A024R3V4 A0A0S2Z5A8 Q9H2H8
PDB IDs			1XYH 2OJU 2OK3 8C6J
Enriched GO Terms of Interacting Partners?		Sin3-type Complex MRNA Metabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process RNA Splicing Negative Regulation Of Proteolysis Involved In Protein Catabolic Process MRNA Processing Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein Localization To Vacuole Regulation Of Translational Initiation RNA Metabolic Process Macromolecule Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Protein O-acetylglucosaminyltransferase Activity Protein Folding Negative Regulation Of Translation Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Aggrephagy Macroautophagy Eukaryotic Translation Elongation Factor 1 Complex MRNA Splicing, Via Spliceosome Spliceosomal Complex Pre-mRNA 3'-splice Site Binding U2AF Complex RNA Processing RNA Splicing, Via Transesterification Reactions Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Nucleic Acid Metabolic Process Carbon Catabolite Regulation Of Transcription Regulation Of Chaperone-mediated Autophagy Nucleoplasm Regulation Of Transcription By Glucose Rhythmic Process Host-mediated Activation Of Viral Genome Replication Double-strand Break Repair Via Classical Nonhomologous End Joining Membraneless Organelle Assembly Host-mediated Perturbation Of Viral Genome Replication NSL Complex
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