CNRIP1 and NSRP1

Number of citations of the paper that reports this interaction (PubMedID 26475744)
0

Data Source:
BioGRID (two hybrid, pull down)

		CNRIP1	NSRP1
Description		cannabinoid receptor interacting protein 1	nuclear speckle splicing regulatory protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Presynapse Glutamatergic Synapse GABA-ergic Synapse	Nucleus Nucleoplasm Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	Protein Binding Type 1 Cannabinoid Receptor Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Regulation Of Signaling Receptor Activity Regulation Of Trans-synaptic Signaling By Endocannabinoid, Modulating Synaptic Transmission Negative Regulation Of Signaling Receptor Activity	Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Processing RNA Splicing Developmental Process
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Systolic blood pressure ( 30578418)	Brain morphology (MOSTest) ( 32665545) QRS complex (12-leadsum) ( 27659466)
Interacting Genes		7 interacting genes: BRCA1 GCH1 GRSF1 NSRP1 PRTFDC1 RUNX1 YIF1A	11 interacting genes: APP CNR1 CNRIP1 CTNNBL1 DISC1 FBXO25 NEDD4 NEDD4L RANBP9 SRPK1 SRPK2
Entrez ID		25927	84081
HPRD ID		12813	08536
Ensembl ID		ENSG00000119865	ENSG00000126653
Uniprot IDs		Q96F85	A0A024QZ33 B7ZL27 Q9H0G5
PDB IDs
Enriched GO Terms of Interacting Partners?			Presynapse Negative Regulation Of Potassium Ion Export Across Plasma Membrane Sodium Channel Inhibitor Activity Potassium Channel Inhibitor Activity Regulation Of Synapse Organization GABA-ergic Synapse Negative Regulation Of Sodium Ion Transport Regulation Of Potassium Ion Export Across Plasma Membrane Ubiquitin Ligase Complex Cytoplasm Receptor Catabolic Process Positive Regulation Of Protein Metabolic Process Enzyme Binding Negative Regulation Of Potassium Ion Transmembrane Transport Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Amyloid Precursor Protein Catabolic Process Neuron Projection Development Negative Regulation Of Potassium Ion Transport Positive Regulation Of Viral Genome Replication Neuromuscular Junction Development Positive Regulation Of Protein Catabolic Process Positive Regulation Of Catabolic Process Glutamatergic Synapse Amyloid-beta Complex Regulation Of Plasma Membrane Bounded Cell Projection Organization Immune Response Regulation Of Amyloid Precursor Protein Catabolic Process Innate Immune Response Growth Cone Lamellipodium Regulation Of Cell Projection Organization Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Neuron Recognition Cell Projection Organization Regulation Of Monoatomic Cation Transmembrane Transport Synapse Organization Receptor Metabolic Process Ubiquitin-protein Transferase Activity Protein Monoubiquitination Formation Of Structure Involved In A Symbiotic Process Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Type 1 Cannabinoid Receptor Binding Protein Metabolic Process Regulation Of Monoatomic Ion Transmembrane Transport Neuron Cellular Homeostasis Regulation Of Dendrite Morphogenesis Positive Regulation Of Viral Process Regulation Of Potassium Ion Transmembrane Transport
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