SPEF1 and KIZ

		SPEF1	KIZ
Description		sperm flagellar 1	kizuna centrosomal protein
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytoskeleton Microtubule Plasma Membrane Microvillus Cilium Axoneme Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium Filopodium Motile Cilium Cell Projection Ciliary Tip 9+2 Motile Cilium Plasma Membrane Bounded Cell Projection Axonemal Central Apparatus	Cytoplasm Centrosome Cytoskeleton Cell Projection
	Molecular Function	Actin Binding Protein Binding Microtubule Binding Cytoskeletal Protein Binding	Protein Binding Protein Kinase Binding
	Biological Process	Microtubule Bundle Formation Cilium Movement Negative Regulation Of Microtubule Depolymerization Cell Migration Cell Projection Organization Lamellipodium Assembly Filopodium Assembly Regulation Of Cytoskeleton Organization Axonemal Central Apparatus Assembly Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway	Spindle Organization
Pathways
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal volume ( 29860282) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Appendicular lean mass ( 33097823) Autism spectrum disorder ( 30804558) Height ( 31562340)
Interacting Genes		6 interacting genes: CFTR CYSRT1 KRT40 KRTAP13-2 PLEKHF2 ZBED1	4 interacting genes: CRYAA MEOX2 TACC3 TFIP11
Entrez ID		25876	55857
HPRD ID		09839	12760
Ensembl ID		ENSG00000101222	ENSG00000088970
Uniprot IDs		Q9Y4P9	A0A087X251 Q2M2Z5
PDB IDs		2EE7
Enriched GO Terms of Interacting Partners?		Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Ventral Spinal Cord Interneuron Fate Determination Type B Pancreatic Cell Fate Commitment Protein Autosumoylation Positive Regulation Of Anion Channel Activity Pancreatic A Cell Fate Commitment Pancreatic PP Cell Fate Commitment Keratin Filament Positive Regulation Of Monoatomic Anion Transport Spinal Cord Oligodendrocyte Cell Fate Specification Positive Regulation Of Enamel Mineralization Oligodendrocyte Cell Fate Specification Transepithelial Water Transport Spinal Cord Oligodendrocyte Cell Differentiation Intermediate Filament Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Glial Cell Fate Specification Structural Molecule Activity Bicarbonate Transmembrane Transporter Activity Early Endosome Membrane Intracellular PH Elevation Response To Ketone Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Type B Pancreatic Cell Differentiation Neuron Fate Determination	Protein-containing Complex Organization Ventral Spinal Cord Interneuron Fate Determination Type B Pancreatic Cell Fate Commitment DGTPase Activity DGTP Binding Triphosphoric Monoester Hydrolase Activity Deoxynucleoside Triphosphate Hydrolase Activity Positive Regulation Of Translational Fidelity TRNA-2-methylthio-N(6)-dimethylallyladenosine(37) Synthase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?