TAFA5 and L3MBTL2

		TAFA5	L3MBTL2
Description		TAFA chemokine like family member 5	L3MBTL histone methyl-lysine binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	G Protein-coupled Receptor Binding Cytokine Activity Receptor Ligand Activity	Chromatin Binding Protein Binding Zinc Ion Binding Histone Binding Metal Ion Binding Histone H4K20me2 Reader Activity Histone H4K20me1 Reader Activity Promoter-specific Chromatin Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Vascular Wound Healing Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation	Chromatin Organization Regulation Of DNA-templated Transcription Ectoderm Development Negative Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Stem Cell Differentiation Stem Cell Proliferation
Pathways			SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS			Adventurousness ( 30643258) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Lamb consumption ( 32066663) Major depressive disorder ( 27479909) Neuroticism ( 27918536 29255261) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		2 interacting genes: GPR37 RNF167	49 interacting genes: AMOTL2 BEND7 BIVM CARD9 CCDC106 CCDC33 CEP76 DRC4 EFHC2 EIF4ENIF1 FAM217B GKAP1 GOLGA2 GPRASP3 H3C1 H4C1 HSF2BP LNX2 MEAF6 MEOX1 MPP3 NRF1 PAICS PHF10 PIAS1 PICK1 POU6F2 PRKAR1B RBAK REL SSUH2 STAC3 STAM2 TAX1BP1 TBC1D9B TEKT1 THAP1 THAP11 TLE5 TNNI1 TRIM42 TRIM50 TSPYL1 ZBTB26 ZBTB48 ZFP64 ZFY ZNF467 ZNF829
Entrez ID		25817	83746
HPRD ID		13295	13954
Ensembl ID		ENSG00000219438	ENSG00000100395
Uniprot IDs		Q7Z5A7	A0A0S2Z5X6 Q969R5
PDB IDs			2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?		Prosaposin Receptor Activity Positive Regulation Of Dopamine Metabolic Process Locomotion Involved In Locomotory Behavior Histone H4K20me1 Reader Activity Histone H4K20me2 Reader Activity Dopamine Biosynthetic Process Regulation Of Dopamine Metabolic Process Catecholamine Biosynthetic Process Neuropeptide Receptor Activity Endolysosome Membrane Cellular Response To Leucine Starvation Protein K29-linked Ubiquitination Ectoderm Development Neuropeptide Binding Protein K6-linked Ubiquitination Peptide Binding Dopamine Metabolic Process Amine Biosynthetic Process Biogenic Amine Biosynthetic Process G Protein-coupled Peptide Receptor Activity Dendrite Development Catecholamine Metabolic Process Organelle Membrane	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?