GCSAM and BTLA

		GCSAM	BTLA
Description		germinal center associated signaling and motility	B and T lymphocyte associated
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	Actin Binding Protein Binding Protein Kinase Binding Myosin II Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Regulation Of B Cell Receptor Signaling Pathway Regulation Of Lymphocyte Migration Negative Regulation Of Lymphocyte Migration	Adaptive Immune Response Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of T Cell Proliferation
Pathways			Co-inhibition by BTLA Co-inhibition by BTLA
Drugs
Diseases
GWAS			Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		4 interacting genes: AP1M1 APPBP2 CNOT2 CYSRT1	4 interacting genes: PTPN11 PTPN6 TNFRSF14 VTCN1
Entrez ID		257144	151888
HPRD ID		09695	06392
Ensembl ID		ENSG00000174500	ENSG00000186265
Uniprot IDs		Q8N6F7	Q400G7 Q7Z6A9
PDB IDs			2AW2 6NYP 8F60 8F6L 8F6O
Enriched GO Terms of Interacting Partners?			Negative Regulation Of T Cell Proliferation Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Leukocyte Proliferation Negative Regulation Of T Cell Activation Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Immune System Process Regulation Of T Cell Proliferation Negative Regulation Of Lymphocyte Activation Negative Regulation Of Leukocyte Activation Positive Regulation Of Cell Adhesion T Cell Costimulation Negative Regulation Of Cell-cell Adhesion Negative Regulation Of Cell Activation Regulation Of Mononuclear Cell Proliferation Positive Regulation Of T Cell Activation Regulation Of Leukocyte Proliferation Positive Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Neutrophil Activation Negative Regulation Of Cell Adhesion Regulation Of Cell Adhesion Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Lymphocyte Activation Regulation Of Neutrophil Activation Non-membrane Spanning Protein Tyrosine Phosphatase Activity Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Neutrophil Activation Involved In Immune Response Regulation Of Immune Response Regulation Of Cell-cell Adhesion Positive Regulation Of Cytokine Production Regulation Of Lymphocyte Activation Negative Regulation Of Multicellular Organismal Process Peptidyl-tyrosine Dephosphorylation Platelet Formation Megakaryocyte Development Regulation Of B Cell Receptor Signaling Pathway Regulation Of Lipopolysaccharide-mediated Signaling Pathway Neutrophil Activation Regulation Of Cell Activation Negative Regulation Of Cell Population Proliferation Regulation Of Immune System Process Regulation Of Type I Interferon-mediated Signaling Pathway Phosphotyrosine Residue Binding Regulation Of Cytokine Production Regulation Of Cell Adhesion Mediated By Integrin Myeloid Cell Development Regulation Of Lymphocyte Migration Positive Regulation Of Immune System Process
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