LMNTD2 and TBC1D25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LMNTD2	TBC1D25
Description		lamin tail domain containing 2	TBC1 domain family member 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lamin Filament	Cytoplasm Autophagosome Cytoplasmic Vesicle
	Molecular Function	Protein Binding Structural Constituent Of Chromatin	GTPase Activator Activity Protein Binding
	Biological Process		Autophagy Regulation Of Autophagosome Maturation
Pathways			TBC/RABGAPs
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 26502338)
Interacting Genes		18 interacting genes: C3orf62 CYSRT1 FBLN1 INCA1 KHDRBS2 KHDRBS3 KRT27 KRT31 KRTAP12-3 KRTAP5-2 KRTAP9-2 KRTAP9-3 MID2 NBPF19 NOTCH2NLA RBMY1A1 TBC1D25 TRAF1	17 interacting genes: FAM9B FEZ1 FEZ2 GABARAP GABARAPL1 GABARAPL2 HMGB2 KCNIP1 LARP1B LGALS14 LMNTD2 MAP1LC3A MAP1LC3B MAP1LC3C RAB2A RUSC1 TRIML2
Entrez ID		256329	4943
HPRD ID		14600	08948
Ensembl ID		ENSG00000185522	ENSG00000068354
Uniprot IDs		Q8IXW0	B4DF03 Q3MII6
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Identical Protein Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Membrane Autophagosome Maturation Mitophagy Autophagy Of Mitochondrion Macroautophagy Autophagosome Autophagosome Assembly Autophagosome Organization Phospholipid Binding Protein-containing Complex Disassembly Autophagy Vacuole Organization Cellular Response To Starvation Microtubule Response To Starvation Cellular Response To Nutrient Levels Ubiquitin Protein Ligase Binding GABA Receptor Binding Cytoplasmic Vesicle Organelle Assembly Response To Nutrient Levels Beta-tubulin Binding Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Organelle Membrane Cytoskeleton Organelle Organization Negative Regulation Of Autophagosome Assembly Cellular Response To Stress Microtubule Binding Endomembrane System Positive Regulation Of Protein Polyubiquitination Transcription Factor Binding Extrinsic Apoptotic Signaling Pathway Cytoplasm Protein-containing Complex Organization Regulation Of Protein Polyubiquitination Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Catabolic Process Gamma-tubulin Binding Negative Regulation Of Macroautophagy Positive Regulation Of Interferon-beta Production Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Autophagosome Assembly Cellular Component Assembly Regulation Of Interferon-beta Production Golgi Apparatus Regulation Of Vacuole Organization
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