YTHDF3 and GGH

		YTHDF3	GGH
Description		YTH N6-methyladenosine RNA binding protein F3	gamma-glutamyl hydrolase
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GO Annotations	Cellular Component	P-body Cytoplasm Cytosol Cytoplasmic Stress Granule	Extracellular Region Extracellular Space Nucleus Lysosome Vacuole Azurophil Granule Lumen Specific Granule Lumen Melanosome Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Reader Activity	Protein Binding Exopeptidase Activity Omega Peptidase Activity Hydrolase Activity Gamma-glutamyl-peptidase Activity
	Biological Process	Stress Granule Assembly Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Translational Initiation Negative Regulation Of Type I Interferon-mediated Signaling Pathway MRNA Destabilization Organelle Assembly Regulation Of Trophoblast Cell Migration	Tetrahydrofolylpolyglutamate Metabolic Process
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Breakfast cereal skipping frequency ( 31190057) Breakfast skipping ( 31190057) Chronotype ( 30696823) HDL cholesterol levels ( 32203549) Myocardial infarction ( 26708285) Schizophrenia ( 33169155) Smoking behaviour (cigarettes smoked per day) ( 30679032) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)	Blood protein levels ( 30072576)
Interacting Genes		17 interacting genes: ALG13 ANKHD1 CPSF7 CTTN DMRTB1 EXOSC5 FAF1 LARP4 NMD3 PRRC2B QKI RBFOX2 RBM22 RPS21 SF1 SNRPA ZDHHC17	2 interacting genes: LIG4 SGTB
Entrez ID		253943	8836
HPRD ID		08106	03299
Ensembl ID		ENSG00000185728	ENSG00000137563
Uniprot IDs		A0A024R7W5 A0A087WY31 B4DPX9 Q7Z739 Q8NA80	A0A7I2V5X9 Q92820
PDB IDs		6ZOT 8BS5 8BS6	1L9X
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing MRNA Metabolic Process MRNA Processing RNA Splicing RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome MRNA Binding Cytosolic Small Ribosomal Subunit Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Nucleic Acid Metabolic Process Spliceosomal Complex Gamma-glutamyl-peptidase Activity Regulation Of RNA Splicing Internal N(7)-methylguanine-containing RNA Reader Activity Perforant Pathway To Dendrate Granule Cell Synapse Methionine Adenosyltransferase Regulator Activity N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Activity Macromolecule Metabolic Process	Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency T Cell Differentiation Central Nervous System Development DNA Ligase Activity DN2 Thymocyte Differentiation TRC Complex Olfactory Nerve Development Right Ventricular Compact Myocardium Morphogenesis Right Ventricular Cardiac Muscle Tissue Morphogenesis Ear Morphogenesis Double-strand Break Repair Via Classical Nonhomologous End Joining Lymphoid Progenitor Cell Differentiation Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development DNA-dependent Protein Kinase-DNA Ligase 4 Complex Single Strand Break Repair Immunoglobulin V(D)J Recombination AMP Binding Lymphocyte Differentiation Chordate Embryonic Development Nonhomologous End Joining Complex Nucleotide-excision Repair, DNA Gap Filling In Utero Embryonic Development T Cell Activation Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Secondary Palate Development Regulation Of Growth Hormone Secretion Semicircular Canal Morphogenesis Ventricular Compact Myocardium Morphogenesis Adult Heart Development Olfactory Behavior Atrioventricular Canal Development Nose Development Phosphatidylinositol Bisphosphate Binding N6-methyladenosine-containing RNA Reader Activity Ventricular Trabecula Myocardium Morphogenesis Cellular Response To Lithium Ion Mononuclear Cell Differentiation Response To Lithium Ion Regulation Of Metal Ion Transport Female Genitalia Development Chemosensory Behavior Regulation Of Trophoblast Cell Migration
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