ABCA4 and CNGB1

Number of citations of the paper that reports this interaction (PMID 10466724)
25

Data Source:
HPRD (in vivo)

		ABCA4	CNGB1
Gene Name		ATP-binding cassette, sub-family A (ABC1), member 4	cyclic nucleotide gated channel beta 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Membrane Photoreceptor Disc Membrane	Golgi Membrane Plasma Membrane Integral Component Of Plasma Membrane Intracellular Cyclic Nucleotide Activated Cation Channel Complex Golgi-associated Vesicle Membrane Terminal Bouton Ciliary Membrane Transmembrane Transporter Complex
	Molecular Function	Phospholipid-translocating ATPase Activity Transporter Activity ATP Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances	Intracellular CAMP Activated Cation Channel Activity Intracellular CGMP Activated Cation Channel Activity Voltage-gated Potassium Channel Activity Protein Binding Ligand-gated Ion Channel Activity CAMP Binding CGMP Binding
	Biological Process	Retinoid Metabolic Process Phospholipid Transfer To Membrane Transport Visual Perception Phototransduction, Visible Light Phospholipid Translocation Photoreceptor Cell Maintenance Transmembrane Transport	Retina Homeostasis Transport Cation Transport Organelle Organization Visual Perception Phototransduction, Visible Light Sensory Perception Of Smell Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Protein Localization To Organelle Regulation Of Membrane Potential Photoreceptor Cell Maintenance Detection Of Light Stimulus Involved In Visual Perception Protein Heterotetramerization Cytosolic Calcium Ion Homeostasis Potassium Ion Transmembrane Transport
Pathways		ABC-family proteins mediated transport Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Retinoid cycle disease events Diseases associated with visual transduction	Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Visual phototransduction The phototransduction cascade VxPx cargo-targeting to cilium Assembly of the primary cilium Diseases associated with visual transduction
Drugs
Diseases
GWAS		D-dimer levels ( 21502573) Dialysis-related mortality ( 21546767) Palmitoleic acid (16:1n-7) plasma levels ( 23362303)
Protein-Protein Interactions		1 interactors: CNGB1	3 interactors: ABCA4 PNN PRPH2
Entrez ID		24	1258
HPRD ID		03408	07204
Ensembl ID		ENSG00000198691	ENSG00000070729
Uniprot IDs		P78363 Q6AI28	Q14028
PDB IDs
Enriched GO Terms of Interacting Partners?		Detection Of Light Stimulus Involved In Visual Perception Protein Heterotetramerization Regulation Of Rhodopsin Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Photoreceptor Cell Maintenance Retina Homeostasis Phototransduction, Visible Light Detection Of Visible Light Phototransduction Cellular Response To Light Stimulus Protein Tetramerization Detection Of Light Stimulus Protein Heterooligomerization Cellular Response To Radiation Visual Perception Detection Of Abiotic Stimulus Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Sensory Perception Of Light Stimulus Tissue Homeostasis Cytosolic Calcium Ion Homeostasis Potassium Ion Transmembrane Transport Potassium Ion Transport Multicellular Organismal Homeostasis Regulation Of Membrane Potential Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Response To Light Stimulus Sensory Perception Of Smell Cellular Metal Ion Homeostasis Sensory Perception Of Chemical Stimulus Detection Of Stimulus Involved In Sensory Perception Regulation Of Ion Transmembrane Transport Protein Oligomerization Cellular Cation Homeostasis Response To Radiation Cellular Ion Homeostasis Metal Ion Homeostasis Protein Localization To Organelle Cellular Chemical Homeostasis Ion Homeostasis Detection Of Stimulus Regulation Of Ion Transport	Visual Perception Sensory Perception Of Light Stimulus Phospholipid Transfer To Membrane Response To Low Light Intensity Stimulus Response To Light Stimulus Response To Radiation Response To Light Intensity Sensory Perception Photoreceptor Cell Maintenance Response To Abiotic Stimulus Neurological System Process Phospholipid Translocation Cell Adhesion Retina Homeostasis
Tagcloud ?		allelic audiogram bbs1 c2orf71 cerkl crb1 decisive deepen denaturing dhplc discern dystrophies electrophysiology fundus homozygosity hrm intrafamilial melt mlpa monoallelic ngs pde6b pedigrees rd rdh12 sanger sscp tulp1 ush2a
Tagcloud (Difference) ?		allelic audiogram bbs1 c2orf71 cerkl crb1 decisive deepen denaturing dhplc discern dystrophies electrophysiology fundus homozygosity hrm intrafamilial melt mlpa monoallelic ngs pde6b pedigrees rd rdh12 sanger sscp tulp1 ush2a
Tagcloud (Intersection) ?