DNAAF11 and LRCH3

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		DNAAF11	LRCH3
Name		dynein axonemal assembly factor 11	leucine rich repeats and calponin homology domain containing 3
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Cilium Motile Cilium Cell Projection Apical Cytoplasm Dynein Axonemal Particle	Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Male Gonad Development Flagellated Sperm Motility Outer Dynein Arm Assembly Inner Dynein Arm Assembly Motile Cilium Assembly Establishment Of Localization In Cell Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Reproductive System Development Protein Localization To Cilium Axonemal Dynein Complex Assembly Cerebrospinal Fluid Circulation Protein Localization To Motile Cilium	Septin Cytoskeleton Organization
GWAS		No GWAS studies recorded	Airway responsiveness in chronic obstructive pulmonary disease ( 25514360 )
Novel Interactors		1 novel interactors: ST3GAL1	None recorded
Interacting Genes		10 interacting genes: DDX6 LRCH3 LSM2 MEOX2 PLEKHF2 PODN SSX7 TERF1 TSC22D2 TTC23L	4 interacting genes: DGCR6L DNAAF11 MYO6 YWHAG
Entrez ID		23639	84859
HPRD ID		10286	14308
Ensembl ID		ENSG00000129295	ENSG00000186001
Uniprot IDs		Q86X45	B4DU23 Q96II8
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Concave Side Of Sperm Head Viral RNA Genome Packaging Golgi Medial Cisterna Membrane Negative Regulation Of Activated CD8-positive, Alpha-beta T Cell Apoptotic Process Protein Sialylation Golgi Trans Cisterna Membrane Memory B Cell Differentiation Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Shelterin Complex Assembly P-body Beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide Alpha-2,3- Sialyltransferase Somite Specification Ganglioside Biosynthetic Process Via Lactosylceramide Lsm1-7-Pat1 Complex Septin Cytoskeleton Organization Viral Process Beta-galactoside (CMP) Alpha-2,3-sialyltransferase Activity Regulation Of Establishment Of Protein Localization To Telomere Shelterin Complex Outer Dense Fiber Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Activity Ankyrin Repeat Binding Lsm2-8 Complex	None