MIR9-3 and MARS1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR9-3	MARS1
Description		microRNA 9-3	methionyl-tRNA synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex	Nucleus Nucleolus Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Exosome
	Molecular Function		TRNA Binding Nucleotide Binding RNA Binding Aminoacyl-tRNA Ligase Activity Methionine-tRNA Ligase Activity ATP Binding Ligase Activity
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing	Translation TRNA Aminoacylation For Protein Translation Methionyl-tRNA Aminoacylation RRNA Transcription Cellular Response To Platelet-derived Growth Factor Stimulus Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Pathways			Selenoamino acid metabolism Cytosolic tRNA aminoacylation Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Diseases
GWAS		Schizophrenia ( 28991256 30285260)
Interacting Genes		66 interacting genes: ADARB1 APOBEC3B CRTAP DARS1 DDX1 DDX21 DDX3X EIF2AK2 EPRS1 ERAL1 FAM98A FIP1L1 FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LRPPRC MARS1 MATR3 MSI2 NONO P3H1 PDCD11 PRMT1 PTBP1 PUF60 PUM1 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SF3B1 SF3B3 SFPQ STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2B UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346 ZNF385A	81 interacting genes: CASK CEBPA DUX4 ESR1 HNRNPUL1 MAFK MAPK14 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PPM1F RNF10 RPS27 SUMO2 TNNT1
Entrez ID		407051	4141
HPRD ID			08864
Ensembl ID		ENSG00000284329	ENSG00000166986
Uniprot IDs			P56192
PDB IDs			2DJV 4BL7 4BVX 4BVY 5GL7 5GOY 5Y6L
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Ribonucleoprotein Complex Macromolecule Metabolic Process MRNA Binding Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleus Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Catalytic Step 2 Spliceosome Spliceosomal Complex Negative Regulation Of MRNA Catabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Primary Metabolic Process MiRNA Binding Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Negative Regulation Of RNA Catabolic Process TRNA Aminoacylation MRNA Stabilization Regulation Of MRNA Processing Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process RNA Stabilization Regulation Of Metabolic Process Cytoplasmic Stress Granule Negative Regulation Of Macromolecule Metabolic Process TRNA Metabolic Process Regulation Of MRNA Stability Regulation Of Alternative MRNA Splicing, Via Spliceosome CRD-mediated MRNA Stabilization Regulation Of RNA Stability Negative Regulation Of Metabolic Process Ligase Activity Negative Regulation Of Translation	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization RNA Destabilization Negative Regulation Of Translation Positive Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Regulation Of MRNA Stability Negative Regulation Of Cell Migration Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Regulation Of RNA Stability Negative Regulation Of Locomotion Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Angiogenesis Negative Regulation Of Angiogenesis Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Vasculature Development Regulation Of Vasculature Development Regulation Of Translation Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Developmental Process Regulation Of MRNA Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Endothelial Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cell Migration Negative Regulation Of Protein Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Motility Extracellular Space
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