PIGN and ZCCHC2

		PIGN	ZCCHC2
Description		phosphatidylinositol glycan anchor biosynthesis class N	zinc finger CCHC-type containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane	Cytoplasm
	Molecular Function	Transferase Activity Mannose-ethanolamine Phosphotransferase Activity	Nucleic Acid Binding Zinc Ion Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	GPI Anchor Biosynthetic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	A body shape index ( 34021172) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Bipolar disorder ( 31043756 33263727) Breastfeeding duration ( 25475840) Chronotype ( 30696823) Cognitive function in longevity ( 33607172) Menopause (age at onset) ( 29773799) Morning person ( 30696823) Pulse pressure ( 30224653) Serum albumin levels ( 23022100) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		1 interacting genes: FJX1	2 interacting genes: RNF10 SHANK3
Entrez ID		23556	54877
HPRD ID		12085	11696
Ensembl ID		ENSG00000197563	ENSG00000141664
Uniprot IDs		A0A1W2PNR0 A0A1W2PPR7 A0A1W2PQA9 O95427	Q9BRD4 Q9C0B9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Platelet-derived Growth Factor Production Regulation Of Platelet-derived Growth Factor Production Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Cell Proliferation Involved In Kidney Development Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Collagen Biosynthetic Process Retina Layer Formation Regulation Of Collagen Biosynthetic Process Regulation Of Collagen Metabolic Process Serine-type Endopeptidase Inhibitor Activity
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