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PIGN
Description
phosphatidylinositol glycan anchor biosynthesis class N
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Membrane
Molecular Function
Transferase Activity
Mannose-ethanolamine Phosphotransferase Activity
Biological Process
GPI Anchor Biosynthetic Process
Pathways
Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Novel Interacting Genes
2 novel interacting genes:
SERPINB7
ZCCHC2
Interacting Genes
1 interacting genes:
FJX1
Entrez ID
23556
HPRD ID
12085
Ensembl ID
ENSG00000197563
Uniprot IDs
A0A1W2PNR0
A0A1W2PPR7
A0A1W2PQA9
O95427
PDB IDs
Enriched GO Terms of Interacting Partners
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Positive Regulation Of Platelet-derived Growth Factor Production
Regulation Of Platelet-derived Growth Factor Production
Positive Regulation Of Glomerular Mesangial Cell Proliferation
Positive Regulation Of Transforming Growth Factor Beta1 Production
Positive Regulation Of Cell Proliferation Involved In Kidney Development
Regulation Of Glomerular Mesangial Cell Proliferation
Positive Regulation Of Transforming Growth Factor Beta Production
Positive Regulation Of Collagen Biosynthetic Process
Retina Layer Formation
Regulation Of Collagen Biosynthetic Process
Regulation Of Collagen Metabolic Process
Serine-type Endopeptidase Inhibitor Activity
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