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PIGN

Description phosphatidylinositol glycan anchor biosynthesis class N
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Cytosol
  • Plasma Membrane
  • Membrane
Molecular Function
  • Transferase Activity
  • Mannose-ethanolamine Phosphotransferase Activity
Biological Process
  • GPI Anchor Biosynthetic Process
Pathways
  • Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS
  • Metabolite levels ( 23823483)
Novel Interacting Genes 2 novel interacting genes: SERPINB7 ZCCHC2
Interacting Genes 1 interacting genes: FJX1
Entrez ID 23556
HPRD ID 12085
Ensembl ID ENSG00000197563
Uniprot IDs A0A1W2PNR0 A0A1W2PPR7 A0A1W2PQA9 O95427
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Positive Regulation Of Platelet-derived Growth Factor Production
  • Regulation Of Platelet-derived Growth Factor Production
  • Positive Regulation Of Glomerular Mesangial Cell Proliferation
  • Positive Regulation Of Transforming Growth Factor Beta1 Production
  • Positive Regulation Of Cell Proliferation Involved In Kidney Development
  • Regulation Of Glomerular Mesangial Cell Proliferation
  • Positive Regulation Of Transforming Growth Factor Beta Production
  • Positive Regulation Of Collagen Biosynthetic Process
  • Retina Layer Formation
  • Regulation Of Collagen Biosynthetic Process
  • Regulation Of Collagen Metabolic Process
  • Serine-type Endopeptidase Inhibitor Activity
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