NNT and MVP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NNT	MVP
Gene Name		nicotinamide nucleotide transhydrogenase	major vault protein
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Membrane Integral Component Of Membrane	Nucleus Nuclear Pore Cytoplasm Cytoskeleton Membrane Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	NAD(P)+ Transhydrogenase (B-specific) Activity NAD(P)+ Transhydrogenase Activity NAD(P)+ Transhydrogenase (AB-specific) Activity NADP Binding NAD Binding	Protein Binding Protein Kinase Binding Protein Phosphatase Binding
	Biological Process	Tricarboxylic Acid Cycle Proton Transport Cellular Metabolic Process Small Molecule Metabolic Process Cell Redox Homeostasis Oxidation-reduction Process Reactive Oxygen Species Metabolic Process Hydrogen Ion Transmembrane Transport	Cell Proliferation Protein Transport Negative Regulation Of Signaling Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity Protein Activation Cascade
Pathways		Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)
Drugs		NADH Tatp 2\'-Monophosphoadenosine 5\'-Diphosphoribose
Diseases
GWAS
Protein-Protein Interactions		1 interactors: MVP	57 interactors: ADAMTSL4 AES BANP BZRAP1 C1orf94 CALCOCO2 CAMK2B CCDC36 CKAP4 CYTB DISC1 DLX2 EPHX2 ESR1 FAM154A FAM46C GIT2 GOLGA2 HP KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MKL1 NNT NOTCH2NL OBFC1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SERTAD1 SKIL SLC2A4 TCF4 TFCP2 TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 VAC14 ZBTB32 ZMIZ2
Entrez ID		23530	9961
HPRD ID		09715	05475
Ensembl ID		ENSG00000112992	ENSG00000013364
Uniprot IDs		Q13423	B4DP93 Q14764
PDB IDs		1DJL 1PT9 1U31	1Y7X
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Autophosphorylation Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Protein Autophosphorylation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Tyrosine Kinase Activity MRNA Transport RNA Transport RNA Localization Protein Activation Cascade ERBB Signaling Pathway Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation	Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Signaling Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Response To Cytokine RNA Metabolic Process Defense Response Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Immune System Process Nitrogen Compound Metabolic Process Negative Regulation Of Signaling Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Positive Regulation Of Apoptotic Process Protein Localization To Nucleus Positive Regulation Of Programmed Cell Death Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Regulation Of Intracellular Signal Transduction Cellular Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Catalytic Activity
Tagcloud ?		5mm apex axes biorace canal canals cbct centering cone cs4 endodontic file files freshly geometrical mandibular maxillary mounted niti photoshop preparation rotary scanned shaping teeth titanium transportation twisted viewer	afp bleomycin bronchogenic cap chance cisplatin cooperative crs cyclophosphamide doxorubicin eastern ecog efficacious entered est evaluable fluorouracil institution lethal mitomycin modest nscbc october oncology prs regimens shrinkage threatening vinblastine
Tagcloud (Difference) ?		5mm apex axes biorace canal canals cbct centering cone cs4 endodontic file files freshly geometrical mandibular maxillary mounted niti photoshop preparation rotary scanned shaping teeth titanium transportation twisted viewer	afp bleomycin bronchogenic cap chance cisplatin cooperative crs cyclophosphamide doxorubicin eastern ecog efficacious entered est evaluable fluorouracil institution lethal mitomycin modest nscbc october oncology prs regimens shrinkage threatening vinblastine
Tagcloud (Intersection) ?