ARHGAP45 and ZUP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARHGAP45	ZUP1
Description		Rho GTPase activating protein 45	zinc finger containing ubiquitin peptidase 1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Membrane Ruffle Membrane Secretory Granule Lumen Azurophil Granule Lumen Cell Projection	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Cysteine-type Deubiquitinase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Neutrophil degranulation RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: BICD2 GMIP GOLGA2 HSF2BP PIBF1 PPP1R13B RINT1 TRIM50 ZUP1	9 interacting genes: ARHGAP45 CDKN2A CFTR CLN8 MMP14 PRMT5 RPS21 SHCBP1 UBC
Entrez ID		23526	221302
HPRD ID		03097	12840
Ensembl ID		ENSG00000180448	ENSG00000153975
Uniprot IDs		B3KVA9 B3KXW7 F5H1R4 K7ES92 K7ES98 Q8IYN3 Q92619	A0A0S2Z644 Q96AP4
PDB IDs		3D25 3FT3	6EI1 6FGE
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Cell-matrix Adhesion Ligase Inhibitor Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Cellular Response To Genistein Negative Regulation Of GDF15-GFRAL Signaling Pathway Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Radial Spoke Head 2 Maintenance Of Ciliary Planar Beating Movement Pattern Positive Regulation Of Macrophage Apoptotic Process P53 Binding Regulation Of Cellular Localization Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Protein Metabolic Process Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Regulation Of B Cell Activation Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Proteolysis Senescence-associated Heterochromatin Focus Negative Regulation Of Immature T Cell Proliferation In Thymus Regulation Of Cell-matrix Adhesion Apoptotic Process Involved In Mammary Gland Involution Cytoplasm Regulation Of Signal Transduction By P53 Class Mediator Sterol Metabolic Process Cholesterol Metabolic Process Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Positive Regulation Of Monoatomic Anion Transport Somatic Motor Neuron Differentiation Glutamate Reuptake Retinal Rod Cell Apoptotic Process Response To Genistein GDF15-GFRAL Signaling Pathway Response To Hydroxyisoflavone Macropinosome Response To Odorant Histone H4R3 Methyltransferase Activity Peptidyl-arginine N-methylation Positive Regulation Of Dopamine Receptor Signaling Pathway Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Peptidyl-arginine Methylation Radial Spoke Head 1 Radial Spoke Assembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?