SLC44A1 and C11orf58

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		SLC44A1	C11orf58
Description		solute carrier family 44 member 1	chromosome 11 open reading frame 58
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Plasma Membrane Membrane Extracellular Exosome	Cellular_component
	Molecular Function	Choline Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity Ethanolamine Transmembrane Transporter Activity	Molecular_function
	Biological Process	Phosphatidylcholine Biosynthetic Process Choline Transport Ethanolamine Transport Choline Catabolic Process Transmembrane Transport Transport Across Blood-brain Barrier	Biological_process
Pathways		Synthesis of PC Choline catabolism SLC-mediated bile acid transport
Drugs
Diseases
GWAS		Aluminium levels ( 26025379) Behavioral disturbance or psychiatric symptoms in prion disease ( 25897833) Intraocular pressure ( 29617998 30591961) Lung cancer in ever smokers ( 28604730) Menarche (age at onset) ( 19448620) Response to fenofibrate (total cholesterol levels) ( 27002377)	Chronotype ( 30696823) Coronary artery disease ( 33020668) Femoral neck bone mineral density ( 29499414) Heel bone mineral density ( 28869591 30598549) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Lumbar spine bone mineral density ( 29499414) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 32888494) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		3 interacting genes: C11orf58 KCNE3 NUDT21	17 interacting genes: A2M CEBPA CEP126 EEF1G FBN3 MBTPS1 POLR2C PTN RNF19A RPLP1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP TRA2A ZBTB48
Entrez ID		23446	10944
HPRD ID		16197	18069
Ensembl ID		ENSG00000070214	ENSG00000110696
Uniprot IDs		Q8WWI5	O00193
PDB IDs		7WWB
Enriched GO Terms of Interacting Partners?		Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization Regulation Of Potassium Ion Export Across Plasma Membrane Basolateral Part Of Cell Negative Regulation Of Voltage-gated Potassium Channel Activity Intracellular Chloride Ion Homeostasis Negative Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Potassium Ion Export Across Plasma Membrane Paraspeckles Regulation Of Lymphoid Progenitor Cell Differentiation MRNA Cleavage Factor Complex Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway Regulation Of Pro-B Cell Differentiation Positive Regulation Of Hematopoietic Progenitor Cell Differentiation Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway MRNA Alternative Polyadenylation Positive Regulation Of Lymphoid Progenitor Cell Differentiation Positive Regulation Of Pro-B Cell Differentiation Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Ventricular Cardiac Muscle Cell Membrane Repolarization Potassium Ion Export Across Plasma Membrane Protein Heterotetramerization Chloride Ion Homeostasis Membrane Repolarization During Action Potential Ventricular Cardiac Muscle Cell Action Potential Monoatomic Anion Homeostasis Negative Regulation Of Potassium Ion Transmembrane Transport Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Delayed Rectifier Potassium Channel Activity MRNA Cleavage And Polyadenylation Specificity Factor Complex Positive Regulation Of Stem Cell Differentiation Neuronal Cell Body Membrane Negative Regulation Of Transporter Activity Membrane Repolarization Protein Heterooligomerization MRNA 3'-UTR AU-rich Region Binding Negative Regulation Of Potassium Ion Transport MRNA 3'-end Processing Regulation Of Membrane Repolarization Cardiac Muscle Cell Action Potential Involved In Contraction Cellular_component Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential
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