MED13L and MED13

Number of citations of the paper that reports this interaction (PubMedID 15175163)
0

Data Source:
HPRD (in vivo)

		MED13L	MED13
Description		mediator complex subunit 13L	mediator complex subunit 13
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex	Nucleus Nucleoplasm Membrane Mediator Complex CKM Complex
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Vitamin D Receptor Binding Nuclear Thyroid Hormone Receptor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cholesterol Homeostasis Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Initiation By RNA Polymerase II Triglyceride Homeostasis
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases		Transposition of great arteries
GWAS		Blond vs. brown/black hair color ( 30531825) Body size at age 10 ( 32376654) Chronic obstructive pulmonary disease ( 30804561) Cognitive decline rate in late mild cognitive impairment ( 26252872) Colorectal cancer ( 21761138) Colorectal cancer or advanced adenoma ( 30510241) Corneal astigmatism ( 30306274) Diabetic kidney disease ( 26305897) Diastolic blood pressure ( 25249183 29403010) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Heart rate response to recovery post exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Heel bone mineral density ( 30598549) Height ( 28552196 31562340) Hematological and biochemical traits ( 31902109) Hippocampal volume ( 29274321) Hypertension ( 25249183) Left ventricular QRS voltage ( 27195777) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 28166213 26635082) Mean arterial pressure ( 29403010) Nose morphology ( 29921221) PR interval ( 30046033) Pulse pressure ( 30224653) Systolic blood pressure ( 25249183 29403010) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Total body bone mineral density ( 29304378) Urate levels in overweight individuals ( 25811787)	Coffee consumption ( 31046077) Initial pursuit acceleration ( 29064472) Objective response to lithium treatment ( 26503763) PR segment duration ( 24850809)
Interacting Genes		2 interacting genes: MED13 RBM11	9 interacting genes: ENO1 ESR1 LCOR MED12 MED13L MED23 MED9 SREBF1 TSC22D2
Entrez ID		23389	9969
HPRD ID		10579	07229
Ensembl ID		ENSG00000123066	ENSG00000108510
Uniprot IDs		Q71F56	Q9UHV7
PDB IDs			8T9D 8TQ2 8TQC 8TQW 8TRH
Enriched GO Terms of Interacting Partners?			Mediator Complex Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Corepressor Binding RNA Polymerase II Preinitiation Complex Assembly Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Transcription Coregulator Activity Axis Elongation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Biosynthetic Process Regulation Of Metabolic Process Core Mediator Complex Positive Regulation Of RNA Metabolic Process Protein-DNA Complex Assembly Cellular Response To Estradiol Stimulus Positive Regulation Of Macromolecule Metabolic Process Nuclear Estrogen Receptor Binding Transcription Coregulator Binding Positive Regulation Of Metabolic Process Nuclear Receptor Activity Transcription Coactivator Activity Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of MiRNA Transcription Nucleoplasm Regulation Of MiRNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription Elongation By RNA Polymerase II Axis Elongation Involved In Somitogenesis Beta-catenin Binding Regulation Of DNA-templated Transcription Elongation Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Response To Estradiol Prostate Epithelial Cord Elongation
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