MED13L

Gene Name		mediator complex subunit 13-like
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mediator Complex
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS		Colorectal cancer ( 21761138)
Protein-protein Interactions		2 interactors: FBXW7 MED13
Entrez ID		23389
HPRD ID		10579
Ensembl ID		ENSG00000123066
Uniprot IDs		Q71F56
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of SREBP Signaling Pathway Negative Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hepatocyte Proliferation Negative Regulation Of DNA Endoreduplication Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Oxidative Stress-induced Cell Death Regulation Of DNA Endoreduplication Regulation Of Hepatocyte Proliferation Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of ERBB Signaling Pathway Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Sister Chromatid Cohesion Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Notch Signaling Pathway Regulation Of Triglyceride Metabolic Process Positive Regulation Of Protein Tyrosine Kinase Activity Androgen Receptor Signaling Pathway Positive Regulation Of Receptor Activity Negative Regulation Of Lipid Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of Cellular Response To Oxidative Stress Regulation Of Lipid Storage Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To UV Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Neuron Apoptotic Process Regulation Of Notch Signaling Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death Positive Regulation Of Ligase Activity Negative Regulation Of Lipid Metabolic Process Regulation Of ERBB Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Protein Stabilization Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To Light Stimulus Negative Regulation Of DNA Metabolic Process Vasculogenesis Lipid Homeostasis Regulation Of Receptor Activity Regulation Of DNA Replication Positive Regulation Of ERK1 And ERK2 Cascade
Tagcloud ?		16p11 17q21 2p21 acot7 autism auts2 cask categorised cnvs crebbp ctnnd2 delineating exonic grm8 homozygous incidental instrumental iq kb microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed