HAUS5 and YAE1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		HAUS5	YAE1
Description		HAUS augmin like complex subunit 5	YAE1 maturation factor of ABCE1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule HAUS Complex Mitotic Spindle Microtubule	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Centrosome Cycle Regulation Of Microtubule Nucleation Spindle Assembly Cell Division	Protein Maturation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: RGS2 YAE1	18 interacting genes: APP BBS10 CEP126 CHD3 CRMP1 EXOC7 HAUS5 HNRNPA2B1 LTO1 MCF2L METTL18 NACAD NAT14 SERPINA4 SLC25A33 TPD52L1 VIM ZNF579
Entrez ID		23354	57002
HPRD ID		19389	16669
Ensembl ID		ENSG00000249115	ENSG00000241127
Uniprot IDs		O94927	Q9NRH1
PDB IDs		7SQK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Glycine Import Across Plasma Membrane Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Negative Regulation Of Amino Acid Transport Positive Regulation Of Cardiac Muscle Contraction Positive Regulation Of Striated Muscle Contraction Adenylate Cyclase Inhibitor Activity Relaxation Of Cardiac Muscle Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Relaxation Of Smooth Muscle Relaxation Of Vascular Associated Smooth Muscle Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Smooth Muscle Contraction Relaxation Of Muscle Negative Regulation Of Muscle Contraction Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cardiac Muscle Tissue Growth Brown Fat Cell Differentiation G-protein Alpha-subunit Binding Negative Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of Muscle Hypertrophy Negative Regulation Of JNK Cascade Response To Amphetamine Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Organ Growth Positive Regulation Of Heart Contraction Maternal Process Involved In Female Pregnancy Beta-tubulin Binding Negative Regulation Of Cardiac Muscle Hypertrophy Response To Amine Positive Regulation Of Muscle Contraction Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Smooth Muscle Contraction Regulation Of Heart Growth Negative Regulation Of Muscle Cell Differentiation Regulation Of Cardiac Muscle Hypertrophy Regulation Of Amine Transport Regulation Of Cardiac Muscle Contraction Regulation Of Striated Muscle Cell Differentiation Regulation Of Organ Growth Negative Regulation Of Developmental Growth Regulation Of Striated Muscle Contraction Cytoplasmic Side Of Plasma Membrane Negative Regulation Of Transmembrane Transport Response To Ethanol Fat Cell Differentiation Regulation Of JNK Cascade Regulation Of Muscle Cell Differentiation Positive Regulation Of Neuron Projection Development Regulation Of G Protein-coupled Receptor Signaling Pathway
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