CLASP1 and CLIP2

Number of citations of the paper that reports this interaction (PMID 11290329)
107

Data Source:
BioGRID (pull down)

		CLASP1	CLIP2
Gene Name		cytoplasmic linker associated protein 1	CAP-GLY domain containing linker protein 2
Image
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Golgi Apparatus Centrosome Kinetochore Microtubule Cytosol Spindle Microtubule Cytoplasmic Microtubule Cell Cortex Membrane Cortical Microtubule Cytoskeleton Centrosomal Corona Extracellular Vesicular Exosome	Microtubule Associated Complex Cytoplasmic Microtubule Microtubule Plus-end
	Molecular Function	Protein Binding Microtubule Binding Kinetochore Binding Microtubule Plus-end Binding	Microtubule Plus-end Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Bundle Formation Organelle Organization Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Establishment Or Maintenance Of Cell Polarity Axon Guidance Exit From Mitosis Microtubule Organizing Center Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Microtubule Anchoring Establishment Of Spindle Orientation Cell Division
Pathways		Role of Abl in Robo-Slit signaling Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Signaling by Robo receptor Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CLIP2 JAKMIP2 MAPRE1 MAPRE3 YWHAG	5 interactors: CLASP1 CLASP2 DYNLL1 ITSN1 MAX
Entrez ID		23332	7461
HPRD ID		09322	09140
Ensembl ID		ENSG00000074054	ENSG00000106665
Uniprot IDs		A2RU21 B7ZLX3 Q7Z460	A7E2F7 Q9UDT6
PDB IDs		4K92	2CP2 2CP3
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Microtubule Plus-end Binding Positive Regulation Of Protein Binding Mitotic Cell Cycle Process Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Binding Cell Cycle Process Regulation Of Protein Binding Cell Cycle Regulation Of Binding Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Nuclear Division Protein Localization To Microtubule Cell Division Negative Regulation Of Microtubule Polymerization Organelle Organization Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Localization To Cytoskeleton Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Microtubule Polymerization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Organelle Organization Regulation Of Protein Phosphorylation Negative Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Mitochondrion Organization Regulation Of Phosphorylation Regulation Of Microtubule Polymerization Or Depolymerization Cellular Protein Localization Negative Regulation Of Protein Polymerization Regulation Of Phosphorus Metabolic Process Regulation Of Mitochondrion Organization Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity	Microtubule Nucleation Microtubule Polymerization Negative Regulation Of Microtubule Depolymerization Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Or Depolymerization Axon Guidance Microtubule Anchoring Regulation Of Microtubule Polymerization Or Depolymerization Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Negative Regulation Of Protein Complex Disassembly Response To External Stimulus System Development Neuron Projection Morphogenesis Protein Polymerization Regulation Of Protein Depolymerization Microtubule Organizing Center Organization Mitotic Cell Cycle Process G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Complex Disassembly Cell Morphogenesis Involved In Differentiation Mitotic Cell Cycle Microtubule-based Process Multicellular Organismal Development Maintenance Of Protein Location In Cell Regulation Of Microtubule Cytoskeleton Organization Neuron Projection Development Anatomical Structure Development Maintenance Of Protein Location Maintenance Of Location In Cell Nervous System Development Cell Projection Morphogenesis Cell Part Morphogenesis Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule-based Process Anatomical Structure Morphogenesis Regulation Of Organelle Organization Establishment Or Maintenance Of Cell Polarity Neuron Development Apoptotic Process Developmental Process Programmed Cell Death Protein Complex Assembly Cell Cycle Process Cell Death Death Cell Morphogenesis Neuron Differentiation
Tagcloud ?		clip1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm microtubule microtubules movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips tracking vertebrate xenopus
Tagcloud (Difference) ?		clip1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm microtubule microtubules movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips tracking vertebrate xenopus
Tagcloud (Intersection) ?