LRRC73 and GADD45GIP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LRRC73	GADD45GIP1
Description		leucine rich repeat containing 73	GADD45G interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Mitochondrial Translation
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		9 interacting genes: CTDSP1 ENPP7 GADD45GIP1 LNX1 NTAQ1 PICK1 RPP25 SHANK3 TSHZ3	62 interacting genes: ANKRD28 APP AR BPIFA1 CADPS CARD10 CBY2 CCNC CEP70 CSNK2B DRC4 DVL3 EAF1 ENKD1 EXOSC4 FBXO7 GADD45A GADD45B GADD45G GEM GOLGA2 GOLGA6A GOLGA6L9 GPRASP2 HMG20A IKBKG KANK2 KIFC3 KRT27 KRT31 KRT34 KRT40 LDOC1 LRRC73 LZTS2 MAGEA11 MAGEA6 MBD3 MIPOL1 MKRN3 MTUS2 MYG1 MYO15B NFKBID NR4A1 NTAQ1 NUTM1 OIP5 PBX4 PICK1 PNMA1 PRDM6 PSMB1 RBM11 SPTA1 TFIP11 TRAF1 TRIM27 UBC UPF2 WWP2 ZRANB1
Entrez ID		221424	90480
HPRD ID		10167	05519
Ensembl ID		ENSG00000204052	ENSG00000179271
Uniprot IDs		Q3B825 Q5JTD7	Q8TAE8
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Regulation Of Synaptic Plasticity Neuron Projection Organization Dendritic Spine Organization Postsynapse Organization Positive Regulation Of Synaptic Transmission, Glutamatergic Receptor Clustering Protein-N-terminal Glutamine Amidohydrolase Activity Positive Regulation Of Intestinal Cholesterol Absorption Protein-N-terminal Asparagine Amidohydrolase Activity Regulation Of Synaptic Transmission, Glutamatergic Guanylate Kinase-associated Protein Clustering Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Intestinal Lipid Absorption Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation Radial Spoke Head 1 Radial Spoke Assembly Radial Spoke Head 3 Positive Regulation Of Phospholipid Catabolic Process Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Supramolecular Fiber Organization Membrane Curvature Sensor Activity Modulation Of Chemical Synaptic Transmission Positive Regulation Of Synaptic Transmission RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Negative Regulation Of Cell Volume Postsynaptic Density Assembly AMPA Glutamate Receptor Clustering Synaptic Receptor Adaptor Activity Regulation Of Synapse Structural Plasticity NMDA Glutamate Receptor Clustering Sperm Flagellum Cilium Movement Involved In Cell Motility Axonemal Central Apparatus Assembly Radial Spoke Head Positive Regulation Of Ceramide Biosynthetic Process Regulation Of Intestinal Cholesterol Absorption Regulation Of Phospholipid Catabolic Process Lipid Digestion Sphingomyelin Phosphodiesterase Activity Negative Regulation Of Actin Nucleation Regulation Of System Process Vocal Learning Neuron Spine Kinocilium Cilium Movement Ribonuclease MRP Complex Positive Regulation Of Long-term Neuronal Synaptic Plasticity Observational Learning	Protein Binding Positive Regulation Of JNK Cascade Nucleus Structural Constituent Of Skin Epidermis Identical Protein Binding Positive Regulation Of P38MAPK Cascade Intermediate Filament Organization Regulation Of JNK Cascade
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