ZNF438 and HAPLN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF438	HAPLN2
Description		zinc finger protein 438	hyaluronan and proteoglycan link protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Extracellular Region Extracellular Space Extracellular Matrix Node Of Ranvier Synapse Perineuronal Net
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding Hyaluronic Acid Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription	Skeletal System Development Cell Adhesion Central Nervous System Development Establishment Of Blood-nerve Barrier Extracellular Matrix Assembly
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Brain morphology (MOSTest) ( 32665545) Congenital left-sided heart lesions (maternal effect) ( 25138779) Heel bone mineral density ( 30598549) Height ( 25429064 31562340) Multiple sclerosis ( 21833088 31604244) Physiological traits ( 31902109) Pulse pressure ( 27841878) Response to fenofibrate (triglyceride levels) ( 27002377) Rheumatoid arthritis ( 24390342 30423114)
Interacting Genes		68 interacting genes: ACOT7 BACH2 BANP BBC3 BYSL CDCA7L CDK18 CEP19 CYSRT1 DMRT3 DPH3 ESRRG FARS2 FRS3 FXR1 GOLGA2 GOLGA6L9 HAPLN2 KCTD7 KRT40 KRTAP10-1 LGALS14 MAGOHB MCC MDFI MID2 MORF4L1 MORN3 MRPL11 MTUS2 MYLIP MYO15B NEK6 NXF1 PIBF1 PICK1 PIH1D2 PLEKHN1 PNMA1 PRMT7 PSMB1 RABEP1 RECK RPP25 SCNM1 SET SMARCD1 SPANXN2 SSX2IP SUV39H1 SYT17 TBC1D22B TP53BP2 TRAF2 TRAPPC2 TRAPPC2B TRIM50 TSGA10 TSTD2 YES1 ZBTB8A ZNF143 ZNF17 ZNF202 ZNF526 ZNF629 ZNF648 ZRANB1	47 interacting genes: ASB13 BANP CCDC125 CIDEB EXOSC8 FHL3 FHL5 FNDC3B GOLGA6L9 GPRIN2 KRT15 KRT27 KRT31 KRT33B KRT34 KRT35 KRT37 KRT40 KRT85 KRTAP10-8 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP6-2 KRTAP6-3 KRTAP9-2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OIP5 PFDN5 PM20D2 PNMA1 PNMA2 PPP1R16B PSTPIP1 SEC13 SSC4D TFCP2 TRIM23 TRIM27 VWC2 ZMYND12 ZNF438 ZNF655
Entrez ID		220929	60484
HPRD ID		11247	17088
Ensembl ID		ENSG00000183621	ENSG00000132702
Uniprot IDs		Q5T427 Q7Z4V0	B7Z1R1 Q9GZV7
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Identical Protein Binding Cytoskeleton Organization Epidermis Development Keratinization Negative Regulation Of Viral Transcription COPII Vesicle Coat Suppression Of Viral Release By Host Protein Binding COPII-coated Vesicle Cargo Loading Regulation Of Viral Transcription Cytosol Cytoskeleton
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