ALAS2 and BANP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ALAS2	BANP
Gene Name		5-aminolevulinate synthase 2	BTG3 associated nuclear protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Nucleoplasm
	Molecular Function	5-aminolevulinate Synthase Activity Protein Binding Glycine Binding Pyridoxal Phosphate Binding Coenzyme Binding	P53 Binding DNA Binding Protein Binding
	Biological Process	Response To Hypoxia Porphyrin-containing Compound Metabolic Process Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Cellular Iron Ion Homeostasis Erythrocyte Differentiation Oxygen Homeostasis Hemoglobin Biosynthetic Process Small Molecule Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Multicellular Organismal Development Chromatin Modification Protein Localization To Nucleus Negative Regulation Of Protein Catabolic Process
Pathways		Heme biosynthesis Metabolism of porphyrins
Drugs		Glycine
Diseases
GWAS			Central corneal thickness ( 20719862) Corneal structure ( 23291589)
Protein-Protein Interactions		4 interactors: BANP GRB2 RABGGTB SUCLA2	77 interactors: ADAM15 ALAS2 BAG5 BTG3 C1orf94 C22orf39 C6orf165 CAMK2D CCDC26 CEP76 COL10A1 DCDC2B DNAJA4 EPHA10 FAM117B FAM120C FAM71C FAM90A1 FHL2 FOXM1 FOXR1 GFM2 HMGB3P1 ISCU L3MBTL3 LACE1 LENG1 LGALS14 LINC00152 LINC01547 LMO2 LMO3 LMO4 LSM2 MAP2K1 MAX MIR4435-1HG MRPL28 MVP NEDD9 NRIP2 PHF21A PID1 PIM1 PML POGZ POLDIP3 POLR2L PPIB PPIC PPIF PRKAB2 PRKCH PRPF39 PSMD9 RAB3IP RBM39 RBPMS RIMS3 SH3RF2 SLC16A3 SNRPB SP2 SPACA6P TERF2 TERF2IP TNXB TOX4 TP53 TRAF2 TRAF4 TROAP ZC2HC1C ZMIZ2 ZNF471 ZNF488 ZNF581
Entrez ID		212	54971
HPRD ID		02356	16538
Ensembl ID		ENSG00000158578	ENSG00000172530
Uniprot IDs		P22557	B3KM38 B4DE54 Q8N9N5 Q9NSS6
PDB IDs
Enriched GO Terms of Interacting Partners?		Succinyl-CoA Pathway Uroporphyrinogen III Biosynthetic Process	Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Metabolic Process Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Cellular Senescence Negative Regulation Of Telomere Maintenance Regulation Of Cell Cycle Negative Regulation Of DNA Metabolic Process Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of Cellular Process Regulation Of Telomere Maintenance Nitrogen Compound Metabolic Process Metabolic Process Regulation Of Cell Cycle Process Cellular Nitrogen Compound Metabolic Process Cell Aging Protection From Non-homologous End Joining At Telomere Positive Regulation Of Cellular Metabolic Process Regulation Of Double-strand Break Repair Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Phosphorylation Transcription From RNA Polymerase II Promoter Positive Regulation Of Signal Transduction Telomere Capping Nucleobase-containing Compound Metabolic Process Negative Regulation Of Mitochondrion Organization Regulation Of Cellular Component Organization Regulation Of Mitotic Cell Cycle Regulation Of Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage Protein Localization To Chromosome, Telomeric Region Regulation Of Stress-activated MAPK Cascade Regulation Of Histone Deacetylation
Tagcloud ?		abcb7 advance asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon hnrnpd leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Difference) ?		abcb7 advance asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon hnrnpd leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Intersection) ?