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ALAS2
Description
5'-aminolevulinate synthase 2
Image
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Membrane
Molecular Function
5-aminolevulinate Synthase Activity
Protein Binding
Transferase Activity
Acyltransferase Activity
Pyridoxal Phosphate Binding
Biological Process
Response To Hypoxia
Porphyrin-containing Compound Metabolic Process
Protoporphyrinogen IX Biosynthetic Process
Heme Biosynthetic Process
Heme B Biosynthetic Process
Intracellular Iron Ion Homeostasis
Erythrocyte Differentiation
Intracellular Oxygen Homeostasis
Tetrapyrrole Biosynthetic Process
Hemoglobin Biosynthetic Process
Erythrocyte Development
Pathways
Heme biosynthesis
Drugs
Pyridoxal phosphate
Glycine
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular hemoglobin concentration (
32888494
)
Mean corpuscular volume (
32888494
)
Red blood cell count (
32888494
)
Red cell distribution width (
32888494
)
Interacting Genes
4 interacting genes:
BANP
GRB2
RABGGTB
SUCLA2
Entrez ID
212
HPRD ID
02356
Ensembl ID
ENSG00000158578
Uniprot IDs
P22557
PDB IDs
5QQQ
5QQR
5QQS
5QQT
5QQU
5QQV
5QQW
5QQX
5QQY
5QQZ
5QR0
5QR1
5QR2
5QR3
5QR4
5QR5
5QR6
5QR7
5QR8
5QR9
5QRA
5QRB
5QRC
5QRD
5QRE
5QT3
6HRH
Enriched GO Terms of Interacting Partners
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Guanyl-nucleotide Exchange Factor Adaptor Activity
Grb2-EGFR Complex
Succinyl-CoA Pathway
Succinate-CoA Ligase Complex
Succinate-CoA Ligase Complex (ADP-forming)
Rab-protein Geranylgeranyltransferase Complex
Rab Geranylgeranyltransferase Activity
Protein Geranylgeranyltransferase Activity
Succinate-CoA Ligase (ADP-forming) Activity
Protein Prenyltransferase Activity
Succinyl-CoA Catabolic Process
Neurotrophin TRKA Receptor Binding
Protein Geranylgeranylation
Branching Involved In Labyrinthine Layer Morphogenesis
Catalytic Activity
Prenyltransferase Activity
Protein Prenylation
Succinyl-CoA Metabolic Process
Succinate Metabolic Process
Insulin Receptor Substrate Binding
Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
Tagcloud
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