SENP5 and RABGAP1

Number of citations of the paper that reports this interaction (PMID 16608850)
61

Data Source:
BioGRID (enzymatic study)

		SENP5	RABGAP1
Gene Name		SUMO1/sentrin specific peptidase 5	RAB GTPase activating protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Intracellular Membrane-bounded Organelle	Centrosome Cytosol Microtubule Associated Complex
	Molecular Function	Protein Binding Cysteine-type Peptidase Activity	DNA Binding GTPase Activator Activity Rab GTPase Activator Activity Protein Binding Tubulin Binding Rab GTPase Binding
	Biological Process	Proteolysis Cell Cycle Protein Sumoylation Post-translational Protein Modification Cellular Protein Metabolic Process Cell Division	Cell Cycle Positive Regulation Of Rab GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		SUMO is proteolytically processed Post-translational protein modification SUMOylation Processing and activation of SUMO
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: RABGAP1 SUMO2 SUMO3	9 interactors: CARM1 DISC1 GABARAPL1 MAP1LC3A RAB4A RAB6A RAB6B SENP1 SENP5
Entrez ID		205564	23637
HPRD ID		10222	06575
Ensembl ID		ENSG00000119231	ENSG00000011454
Uniprot IDs		B4DY82 Q96HI0	Q9Y3P9
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Post-translational Protein Modification Positive Regulation Of Protein Catabolic Process Peptidyl-lysine Modification Positive Regulation Of Proteolysis Regulation Of Protein Catabolic Process Protein Modification By Small Protein Conjugation Regulation Of Proteolysis Positive Regulation Of Metabolic Process Peptidyl-amino Acid Modification Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Protein Localization To Nucleus	Rab Protein Signal Transduction Nucleophagy Protein Sumoylation Mitochondrion Degradation Ras Protein Signal Transduction Retrograde Vesicle-mediated Transport, Golgi To ER Cell Communication Organelle Disassembly Autophagic Vacuole Assembly Intra-Golgi Vesicle-mediated Transport Macroautophagy Cellular Response To Stimulus Peptidyl-amino Acid Modification Retrograde Transport, Endosome To Golgi Histone H3-R17 Methylation Vacuole Organization Histone H3-R2 Methylation Cellular Protein Localization Membrane Fusion Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Cellular Response To Starvation Response To Stimulus Small GTPase Mediated Signal Transduction Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Protein Desumoylation Regulation Of Definitive Erythrocyte Differentiation Autophagy Protein Methylation Cellular Response To Nutrient Levels Response To Starvation Post-translational Protein Modification Endosomal Transport Cellular Response To Extracellular Stimulus Membrane Organization Intracellular Signal Transduction Protein Localization Early Endosome To Golgi Transport Peptidyl-lysine Modification Intracellular Protein Transport Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Golgi Vesicle Transport Antigen Processing And Presentation Signal Transduction Positive Regulation Of Proteolysis Peptidyl-arginine N-methylation Cellular Response To Nitrogen Starvation Mitochondrial Calcium Ion Homeostasis Intracellular Estrogen Receptor Signaling Pathway Signaling
Tagcloud ?			akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?			akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?