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SENP5

Description SUMO specific peptidase 5
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Nucleolus
  • Presynaptic Cytosol
  • Postsynaptic Cytosol
Molecular Function
  • Protein Binding
  • Peptidase Activity
  • Cysteine-type Peptidase Activity
  • Hydrolase Activity
  • DeSUMOylase Activity
  • SUMO-specific Endopeptidase Activity
Biological Process
  • Proteolysis
  • Protein Sumoylation
  • Protein Desumoylation
  • Cell Division
Pathways
  • SUMO is proteolytically processed
Drugs
Diseases
GWAS
  • Gestational age at birth (child effect) ( 31194736)
  • Malaria ( 31844061)
  • Night sleep phenotypes ( 27126917)
Interacting Genes 3 interacting genes: RABGAP1 SUMO2 SUMO3
Entrez ID 205564
HPRD ID 10222
Ensembl ID ENSG00000119231
Uniprot IDs B2R9F5 Q96HI0
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Protein Tag Activity
  • Ubiquitin-like Protein Ligase Binding
  • Protein Sumoylation
  • PML Body
  • Negative Regulation Of DNA Binding
  • SUMO Transferase Activity
  • Protein Modification By Small Protein Conjugation
  • Presynaptic Cytosol
  • Postsynaptic Cytosol
  • Regulation Of DNA Binding
  • Post-translational Protein Modification
  • Hippocampal Mossy Fiber To CA3 Synapse
  • Microtubule Associated Complex
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