OXER1 and EFCAB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OXER1	EFCAB3
Description		oxoeicosanoid receptor 1	EF-hand calcium binding domain 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Pathways		Eicosanoid ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18821565) Breastfeeding duration ( 25475840) Hyperactive-impulsive symptoms ( 18821565)	Objective response to lithium treatment ( 26503763)
Interacting Genes		47 interacting genes: ANAPC11 ARRB2 ASB13 ATG9A CCNK CRYBA2 EFCAB3 ESRP1 FOXH1 HNF1B HNRNPH1 INTS11 JMJD7 KRTAP12-3 KRTAP19-5 KRTAP4-2 KRTAP5-6 KRTAP6-2 KRTAP6-3 LASP1 MED25 NCS1 NEK8 NOC4L OTX1 PLSCR4 PRKAB2 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 RAMAC RBFOX2 RECK RNF208 RNF38 RNF44 TFG TLE5 TP53BP1 VGLL3 ZBTB32 ZC3H10 ZIC1	9 interacting genes: CBY2 GPRASP2 HPRT1 KRT34 KRT35 OXER1 SPECC1L TTC23 WWP2
Entrez ID		165140	146779
HPRD ID		17812	08077
Ensembl ID		ENSG00000162881	ENSG00000172421
Uniprot IDs		Q8TDS5	Q8N7B9
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament	Guanine Salvage Hypoxanthine Salvage Hypoxanthine Phosphoribosyltransferase Activity Guanine Phosphoribosyltransferase Activity Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Neural Crest Cell Delamination 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding Adenine Metabolic Process Hypoxanthine Biosynthetic Process Hypoxanthine Metabolic Process Anterior Neural Tube Closure Guanine Metabolic Process GMP Salvage GMP Catabolic Process IMP Salvage Positive Regulation Of Dopamine Metabolic Process AMP Salvage Intermediate Filament Negative Regulation Of Potassium Ion Export Across Plasma Membrane Purine Ribonucleoside Salvage Structural Molecule Activity
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