ARL6IP6 and GPR61

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARL6IP6	GPR61
Description		ARF like GTPase 6 interacting protein 6	G protein-coupled receptor 61
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Membrane	Endosome Plasma Membrane Endosome Membrane Membrane Receptor Complex
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Protein Binding Arrestin Family Protein Binding
	Biological Process		Signal Transduction G Protein-coupled Receptor Signaling Pathway Ligand-independent Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Lung cancer ( 28604730) Pancreatic cancer ( 29422604) Recurrent major depressive disorder x sex interaction ( 34099189) Refractive error ( 32231278)	Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Chronotype ( 30696823) Hepcidin/ferritin ratio ( 27846281) Morning person ( 30696823) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Stearic acid (18:0) levels ( 23362303) Waist circumference ( 25673412)
Interacting Genes		17 interacting genes: APP AQP6 ARL6 CLRN2 CMTM2 DRD2 EBP GJA8 GPR61 MGST3 RUSF1 SLC10A1 TBXA2R TIMMDC1 TMEM205 TMEM80 TMEM86B	20 interacting genes: APP ARL6IP6 ARLN ATP6V0B CLDND1 CTXN3 EMP3 FCER1G GJA8 GJB6 KLRC1 PLP1 PMP22 SCN3B SLC12A7 SLC13A4 STRIT1 TMEM147 TMEM218 TRARG1
Entrez ID		151188	83873
HPRD ID		12485	06077
Ensembl ID		ENSG00000177917	ENSG00000156097
Uniprot IDs		A0A8I5KQ30 B3KMZ5 Q8N6S5	G4XH66 Q9BZJ8
PDB IDs			8KGK 8TB0 8TB7
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Plasma Membrane Gap Junction-mediated Intercellular Transport Cell-cell Signaling Signaling Bleb Assembly Intercellular Transport Cell Communication Transmembrane Transport Connexin Complex Gap Junction Channel Activity Chemical Synaptic Transmission Protein Localization To Membrane Gap Junction Trans-synaptic Signaling Synaptic Signaling
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