SLC30A7 and PAX7

		SLC30A7	PAX7
Description		solute carrier family 30 member 7	paired box 7
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Golgi Apparatus Membrane Sarcoplasmic Reticulum Cytoplasmic Vesicle Vesicle Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm Golgi Cis Cisterna Membrane	Chromatin Nucleus
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Monoatomic Cation Transmembrane Transporter Activity Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Monoatomic Ion Transport Monoatomic Cation Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Transmembrane Transport Zinc Ion Transmembrane Transport Zinc Ion Import Into Golgi Lumen	Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Nervous System Development Muscle Organ Development Skeletal Muscle Tissue Development Anatomical Structure Morphogenesis Regulation Of Cell Fate Commitment Regulation Of Gene Expression Skeletal Muscle Satellite Cell Commitment Skeletal Muscle Satellite Cell Differentiation Spinal Cord Association Neuron Differentiation Dorsal/ventral Neural Tube Patterning Negative Regulation Of Apoptotic Process Skeletal Muscle Tissue Regeneration Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment Embryonic Skeletal System Development Cartilage Development Muscle Tissue Morphogenesis Regulation Of Chromatin Organization Positive Regulation Of Myoblast Proliferation
Pathways			Specification of the neural plate border
Drugs
Diseases			Alveolar rhabdomyosarcoma
GWAS		Multiple sclerosis ( 21833088 31604244)	Body mass index ( 23669352) Cortical surface area (visual PC2) ( 32198502) Knee osteoarthritis ( 28916551) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 33898419) Orofacial cleft x maternal periconceptional alcohol use interaction (2df) ( 33937227) Orofacial cleft x maternal periconceptional multivitamin use interaction (2df) ( 33937227) Orofacial cleft x maternal periconceptional smoking interaction (2df) ( 33937227) Orofacial clefts ( 22863734) Percentage gas trapping ( 26030696) Response to amphetamines ( 22952603) Urate levels in lean individuals ( 25811787)
Interacting Genes			14 interacting genes: AIRIM CIB1 CSNK2A1 CT55 FHL1 HIRA HNF1B HOMER3 KRTAP19-7 MAGOHB NEDD4 NFIC NFIX TCAP
Entrez ID		148867	5081
HPRD ID		15369	01331
Ensembl ID		ENSG00000162695	ENSG00000009709
Uniprot IDs		Q8NEW0	P23759
PDB IDs		8J7T 8J7U 8J7V 8J7W 8J7X 8J7Y 8J80
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Satellite Cell Commitment Diphthine Methyl Ester Synthase Activity Skeletal Muscle Satellite Cell Differentiation Protein Histidyl Modification To Diphthamide Spinal Cord Association Neuron Differentiation Dorsal/ventral Neural Tube Patterning Positive Regulation Of Myoblast Proliferation Skeletal Muscle Tissue Regeneration Regulation Of Myoblast Proliferation Regulation Of Chromatin Organization Cell Differentiation In Spinal Cord Neuron Fate Commitment Regulation Of Cell Fate Commitment Embryonic Skeletal System Development Tissue Regeneration Skeletal Muscle Tissue Development Dorsal/ventral Pattern Formation Skeletal Muscle Cell Differentiation	Transmembrane Transporter Binding Negative Regulation Of Macromolecule Biosynthetic Process Protein Targeting Negative Regulation Of Metabolic Process RNA Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Protein Targeting To Vacuole Nucleic Acid Metabolic Process Animal Organ Morphogenesis DNA-templated Transcription Formation Of Structure Involved In A Symbiotic Process Epithelial Tube Formation Mesonephric Duct Formation Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Mesonephric Nephron Morphogenesis Ureteric Bud Elongation Pronephric Nephron Tubule Development Mesenchymal Cell Apoptotic Process Involved In Metanephros Development HIR Complex Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Calcineurin-mediated Signaling Positive Regulation Of Male Germ Cell Proliferation Anatomical Structure Morphogenesis Negative Regulation Of Nucleobase-containing Compound Metabolic Process Establishment Of Protein Localization To Vacuole Regulation Of Growth Regulation Of Potassium Ion Transmembrane Transport Channel Inhibitor Activity Chromatin Hepatoblast Differentiation Regulation Of Pronephros Size Titin-telethonin Complex Titin Z Domain Binding Sarcomerogenesis Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Potassium Ion Transport Phosphothreonine Residue Binding Transcription By RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Branch Elongation Involved In Ureteric Bud Branching Mesonephric Duct Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Skeletal Muscle Myosin Thick Filament Assembly G Protein-coupled Glutamate Receptor Binding Endomitotic Cell Cycle Calcium-dependent Protein Kinase Inhibitor Activity Exon-exon Junction Subcomplex Mago-y14 Zinc Ion Import Into Golgi Lumen Protein Localization To Vacuole
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