FAM163A and TMEM179B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM163A	TMEM179B
Description		family with sequence similarity 163 member A	transmembrane protein 179B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Nucleolus Plasma Membrane Membrane Nuclear Speck Secretory Granule Membrane Azurophil Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Monocyte percentage of white cells ( 32888494) Smoking initiation (ever regular vs never regular) ( 30679032)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: GAD2 RWDD2B TMEM179B	47 interacting genes: ADIPOQ BTN2A2 C1QL4 C2CD2L C3orf52 CCDC167 CCL3L3 CCL4 CCL4L2 CD68 CLCA4 CLCN7 CLDN1 CLDN6 CTXN3 CYB561 DERL3 ERGIC3 FAM163A FATE1 FCER1G FXYD3 GALNT15 GKN1 GPR151 GUCA2A IGFBP5 KRTAP12-2 KTN1 LRP10 LYG1 MARCHF2 MFSD6 PLN SERP2 SLC1A1 SLC22A1 SLC52A1 SLC61A1 STX8 TM4SF19 TMEM14A TMEM236 TMEM237 TMEM242 TMEM47 TRARG1
Entrez ID		148753	374395
HPRD ID		14454	14186
Ensembl ID		ENSG00000143340	ENSG00000185475
Uniprot IDs		Q96GL9	G3V185 Q7Z7N9
PDB IDs
Enriched GO Terms of Interacting Partners?		Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Gamma-aminobutyric Acid Biosynthetic Process L-glutamate Catabolic Process Gamma-aminobutyric Acid Metabolic Process Carbon-carbon Lyase Activity Succinate Metabolic Process Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Dicarboxylic Acid Catabolic Process Carboxy-lyase Activity Glutamate Metabolic Process Pyridoxal Phosphate Binding Glutamine Family Amino Acid Metabolic Process Ficolin-1-rich Granule Membrane Azurophil Granule Membrane Amino Acid Biosynthetic Process Proteinogenic Amino Acid Catabolic Process L-amino Acid Catabolic Process Dicarboxylic Acid Metabolic Process	Membrane Inorganic Anion Transport
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