BCDIN3D and KRT72

		BCDIN3D	KRT72
Description		BCDIN3 domain containing RNA methyltransferase	keratin 72
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Methyltransferase Activity O-methyltransferase Activity RNA Methyltransferase Activity TRNA Methyltransferase Activity Transferase Activity Pre-miRNA Binding Small RNA 2'-O-methyltransferase Activity	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	RNA Methylation MiRNA Metabolic Process TRNA Methylation Pre-miRNA Processing Methylation Negative Regulation Of Pre-miRNA Processing	Keratinization Intermediate Filament Organization
Pathways		MicroRNA (miRNA) biogenesis	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Body mass index ( 19079260 31453325 28892062 25673413 26961502 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index variance ( 31453325) Childhood body mass index ( 33045005) Hand grip strength ( 29691431) Menarche (age at onset) ( 27182965 25231870) Metabolic syndrome ( 31589552) Waist circumference ( 25673412 19557197) Weight ( 19079260)	High density lipoprotein cholesterol levels ( 30498476)
Interacting Genes		1 interacting genes: ZFP2	25 interacting genes: BLOC1S6 HSPB1 KRT13 KRT14 KRT15 KRT16 KRT17 KRT18 KRT19 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 UBC
Entrez ID		144233	140807
HPRD ID		14065	09746
Ensembl ID		ENSG00000186666	ENSG00000170486
Uniprot IDs		Q7Z5W3	B4DXK4 Q14CN4
PDB IDs		6L8U
Enriched GO Terms of Interacting Partners?			Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Cytoskeleton Organization Tissue Morphogenesis Cytoskeleton Organelle Organization Anatomical Structure Morphogenesis Extracellular Exosome Cytosol Cell Differentiation Cellular Developmental Process Hair Cycle Intermediate Filament Cytoskeleton Structural Constituent Of Cytoskeleton Developmental Process Keratinization Epidermis Development Hair Follicle Morphogenesis Cornified Envelope Tissue Development Hair Cycle Process Cell Periphery Keratin Filament Binding Negative Regulation Of Protein Kinase C Signaling Bradykinin Biosynthetic Process Circadian Sleep/wake Cycle
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