KRT72 and KRT28

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT72	KRT28
Description		keratin 72	keratin 28
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Keratinization Intermediate Filament Organization	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Follicle Morphogenesis Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		High density lipoprotein cholesterol levels ( 30498476)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Glucose homeostasis traits ( 25524916)
Interacting Genes		25 interacting genes: BLOC1S6 HSPB1 KRT13 KRT14 KRT15 KRT16 KRT17 KRT18 KRT19 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 UBC	23 interacting genes: ABI3 CCDC196 DEUP1 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT76 KRT79 KRT8 KRT80 KRT81 KRT86 NUP58 UCHL5 USHBP1 WASHC1
Entrez ID		140807	162605
HPRD ID		09746	17245
Ensembl ID		ENSG00000170486	ENSG00000173908
Uniprot IDs		B4DXK4 Q14CN4	Q7Z3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Cytoskeleton Organization Tissue Morphogenesis Cytoskeleton Organelle Organization Anatomical Structure Morphogenesis Extracellular Exosome Cytosol Cell Differentiation Cellular Developmental Process Hair Cycle Intermediate Filament Cytoskeleton Structural Constituent Of Cytoskeleton Developmental Process Keratinization Epidermis Development Hair Follicle Morphogenesis Cornified Envelope Tissue Development Hair Cycle Process Cell Periphery Keratin Filament Binding Negative Regulation Of Protein Kinase C Signaling Bradykinin Biosynthetic Process Circadian Sleep/wake Cycle	Structural Constituent Of Skin Epidermis Keratin Filament Keratinization Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Intermediate Filament Cytoskeleton Extracellular Exosome Cytosol Structural Constituent Of Cytoskeleton Epidermis Development Peptide Cross-linking Intermediate Filament Polymerization
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